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Lack of Significant Variability among Different Methods for Calculating Antimicrobial Days of Therapy

Published online by Cambridge University Press:  02 January 2015

Christine J. Kubin ,
Haomiao Jia ,
Luis R. Alba  and
E. Yoko Furuya
Christine J. Kubin*
Affiliation:
Department of Pharmacy, NewYork-Presbyterian Hospital and Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York
Haomiao Jia
Affiliation:
Department of Biostatistics, Mailman School of Public Health and School of Nursing, Columbia University College of Physicians and Surgeons, New York, New York
Luis R. Alba
Affiliation:
Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, New York
E. Yoko Furuya
Affiliation:
Infection Prevention and Control, NewYork-Presbyterian Hospital and Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York
*
630 West 168th Street, Box 82, Division of Infectious Diseases, New York, NY 10032 ([email protected])
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Abstract

Days of therapy (DOTs) are an important measure to quantify antimicrobial use but may not reflect patients' true antimicrobial exposure. Three methods of calculating DOTs were compared to determine whether including “exposure days,” when antimicrobials are given less frequently than daily due to renal dysfunction, makes a difference.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 33 , Issue 4: Special Topic Issue: Antimicrobial Stewardship , April 2012 , pp. 421 - 423
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2012

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References

1. Shlaes, DM, Gerding, DN, John, JF Jr, et al. Society for Healthcare Epidemiology of America and Infectious Diseases Society of America Joint Committee on the Prevention of Antimicrobial Resistance: guidelines for the prevention of antimicrobial resistance in hospitals. Infect Control Hosp Epidemiol 1997;18(4):275–291.Google Scholar
2. Dellit, TH, Owens, RC, McGowan, JE Jr., et al. Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship. Clin Infect Dis 2007;44(2): 159–177.Google Scholar
3. Polk, RE, Fox, C, Mahoney, A, Letcavage, J, MacDougall, C. Measurement of adult antibacterial drug use in 130 US hospitals: comparison of defined daily dose and days of therapy. Clin Infect Dis 2007;44(5):664–670.CrossRefGoogle ScholarPubMed
4. Division of Infectious Diseases. Clinical References. Columbia University Medical Center Division of Infectious Diseases Web site, http://www.cumc.columbia.edu/dept/id/clinical_References.html. Published June 2011. Accessed December 12, 2011.Google Scholar
5. Zagorski, BM, Trick, WE, Schwartz, DN, et al. The effect of renal dysfunction on antimicrobial use measurements. Clin Infect Dis 2002;35:491–497.Google Scholar