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Klebsiella Pneumoniae Infection on a Rehabilitation Unit: Epidemiologic Typing Methods

Published online by Cambridge University Press:  21 June 2016

W. Thompson ,
L. Romance ,
H. Bialkowska-Hobrazanska ,
R.P. Rennie ,
F. Ashton  and
L.E. Nicolle
W. Thompson
Affiliation:
Section of Infectious Diseases, Departments of Medicine and Medical Microbiology, University of Manitoba, Manitoba
L. Romance
Affiliation:
Infection Control Unit, Health Sciences Centre, Winnipeg, Manitoba
H. Bialkowska-Hobrazanska
Affiliation:
St. Joseph's Health Centre, London, Ontario
F. Ashton
Affiliation:
Department of Microbiology, University of Saskatchewan, Saskatoon, Saskatchewan
L.E. Nicolle*
Affiliation:
Laboratory Centre for Disease Control, Health and Welfare Canada, Ottawa, Ontario
*
Health Sciences Centre, MS673-820 Sherbrook Street, Winnipeg, Manitoba, Canada R3A 1R9
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Abstract

Objective:

To identify factors associated with an increased occurrence of Klebsiella pneumoniae isolation in urine cultures and infected wounds on a rehabilitation unit and to compare typing methods for K pneumoniae isolates.

Design:

Retrospective review of laboratory reports and patient records with case-control study. Analysis of K pneumoniae isolates using capsular serotyping, enzyme electrophoretic typing, ribotyping, and DNA typing.

Setting:

48-bed rehabilitation unit in an 1,100-bed tertiary care teaching hospital in Winnipeg, Manitoba.

Results:

In 1988, 20 (19%) of 106 patients admitted to the rehabilitation unit had K pneumoniae isolated from urine or wound, and in 1989 31 (28%) of 111 patients had Klebsiella isolated. Review of ward practices revealed appropriate written policies but evidence of failure in execution leading to multiple opportunities for transmission among patients. Substantial environmental contamination was not identified, although a common urine graduate may have contributed to some transmission. Individuals with K pneumoniae isolated had a significantly longer duration of stay. Many of these were spinal cord-injured patients and were maintained on intermittent catheterization.

One outbreak strain was identified in epidemiologic typing. Other strains were generally identified in individuals with nonnosocomial acquisition of infection. Comparison of epidemiologic typing methods suggests ribotyping may be the optimal method for typing K pneumoniae strains.

Conclusions:

K pneumoniae was acquired frequently by spinal cord-injured patients with extended admissions, re-emphasizing the importance of both patients and stalf following appropriate infection control practices on rehabilitation wards. Ribotyping was the optimal method for typing K pneumoniae isolates.

Type
Original Articles
Information
Infection Control & Hospital Epidemiology , Volume 14 , Issue 4 , April 1993 , pp. 203 - 210
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1993

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