Hostname: page-component-586b7cd67f-dlnhk Total loading time: 0 Render date: 2024-11-30T20:23:03.220Z Has data issue: false hasContentIssue false

Investigation of an Outbreak of Central Venous Catheter–Associated Bloodstream Infection Due to Contaminated Water

Published online by Cambridge University Press:  02 January 2015

Richard W. Douce*
Affiliation:
Departments of Infectious Diseases, Quito, Ecuador
Jeannete Zurita
Affiliation:
Microbiology, Quito, Ecuador
Olga Sanchez
Affiliation:
Infection Control Committee, Quito, Ecuador
Paul Cardenas Aldaz
Affiliation:
Hospital Vozandes-Quito, and the Institute of Microbiology, Universidad San Francisco de Quito, Quito, Ecuador
*
Casilla 17-17-691, Quito, Ecuador ([email protected])

Abstract

An outbreak of central venous catheter-associated bloodstream infections was reported in a hospital in Ecuador. Commercially produced ampoules of water for injection were found to be contaminated with Burkholderia cepacia and Myroides odoratus. Removal of these ampoules yielded a 10-fold reduction in the incidence of catheter-associated infection.

Type
Concise Communications
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2008

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Held, MR, Begier, EM, Beardsley, DS, et al.Life-threatening sepsis caused by Burkholderia cepacia from contaminated intravenous flush solutions prepared by a compounding pharmacy in another state. Pediatrics 2006;118:e212e215.CrossRefGoogle ScholarPubMed
2.Nasser, RM, Rahi, AC, Haddad, MF, Daoud, Z, Irani-Hakime, N, Almawi, WY. Outbreak of Burkholderia cepacia bacteremia traced to contaminated hospital water used for dilution of an alcohol skin antiseptic. Infect Control Hosp Epidemiol 2004;25:231239.CrossRefGoogle ScholarPubMed
3.Panlilio, AL, Beck-Sague, CM, Siegel, JD, et al. Infections and pseudoinfections due to povidone-iodine solution contaminated with Pseudomonas cepacia. Clin Infect Dis 1992;14:10781083.CrossRefGoogle ScholarPubMed
4.Maki, DG, Weise, CE, Sarafin, HW. A semiquantitative culture method for identifying intravenous-catheter-related infection. N Engl J Med 1977;296:13051309.CrossRefGoogle ScholarPubMed
5.Heath, DG, Hohneker, K, Carriker, C, et al.Six-year molecular analysis of Burkholderia cepacia complex isolates among cystic fibrosis patients at a referral center for lung transplantation. J Clin Microbiol 2002;40:11881193.CrossRefGoogle Scholar
6.Tenover, FC, Arbeit, RD, Goering, RV, et al.Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 1995;33:22332239.Google Scholar
7.O'Grady, NP, Alexander, M, Dellinger, EP, et al.Guidelines for the prevention of intravascular catheter-related infections: Centers for Disease Control and Prevention. MMWR Recomm Rep 2002;51(RR-10):129.Google Scholar
8.Green, BT, Green, K, Nolan, PE. Myroides odoratus cellulitis and bacteremia: case report and review. Scand J Infect Dis 2001;33:932934.Google ScholarPubMed
9.Roberts, LA, Collignon, PJ, Cramp, VB, et al.An Australia-wide epidemic of Pseudomonas pickettii bacteraemia due to contaminated “sterile” water for injection. Med J Aust 1990;152:652655.Google Scholar
10.Moreira, BM, Leobons, MB, Pellegrino, FL, et al.Rabtonia pickettii and Burkholderia cepacia complex bloodstream infections related to infusion of contaminated water for injection. J Hosp Infect 2005;60:5155.Google Scholar