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Genotypic Evolution of Acinetobacter baumannii Strains in an Outbreak Associated With War Trauma

Published online by Cambridge University Press:  02 January 2015

Glenn Wortmann ,
Amy Weintrob ,
Melissa Barber ,
Paul Scott ,
Scott T. Zoll ,
Mark W. Eshoo ,
Rangarajan Sampath ,
David J. Ecker  and
Christian Massire
Glenn Wortmann*
Affiliation:
Infectious Disease Service, Walter Reed Army Medical Center, Washington, DC
Amy Weintrob
Affiliation:
Infectious Disease Service, Walter Reed Army Medical Center, Washington, DC Infectious Disease Clinical Research Program, Bethesda, Maryland
Melissa Barber
Affiliation:
Infectious Disease Service, Walter Reed Army Medical Center, Washington, DC Infectious Disease Clinical Research Program, Bethesda, Maryland
Paul Scott
Affiliation:
Division of Retrovirology, Walter Reed Army Institute of Research, Rockville, Maryland
Scott T. Zoll
Affiliation:
Ibis Biosciences, a subsidiary of Isis Pharmaceuticals, Carlsbad, California
Mark W. Eshoo
Affiliation:
Ibis Biosciences, a subsidiary of Isis Pharmaceuticals, Carlsbad, California
Rangarajan Sampath
Affiliation:
Ibis Biosciences, a subsidiary of Isis Pharmaceuticals, Carlsbad, California
David J. Ecker
Affiliation:
Ibis Biosciences, a subsidiary of Isis Pharmaceuticals, Carlsbad, California
Christian Massire
Affiliation:
Ibis Biosciences, a subsidiary of Isis Pharmaceuticals, Carlsbad, California
*
Infectious Disease Clinic, 6900 Georgia Ave., NW, Walter Reed Army Medical Center, Washington, DC 20307–5001 ([email protected])
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Abstract

The Walter Reed Army Medical Center has experienced an influx of traumatically injured patients either infected or colonized with Acinetobacter baumannii. Using multilocus polymerase chain reaction (PCR) and mass spectrometry to genotype isolates, we found an atypical and evolving strain distribution, distinct from those found at nonmilitary hospitals in the United States.

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 29 , Issue 6 , June 2008 , pp. 553 - 555
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2008

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References

1.Scott, P, Deye, G, Srinivasan, A, et al. An outbreak of multidrug-resistant Acinetobacter baumannii-calcoacetkus complex infection in the US military health care system associated with military operations in Iraq. Clin Infect Dis 2007;44:1577–1584.Google Scholar
2.Petersen, K, Riddle, M, Danko, J, et al. Trauma-related infections in battlefield casualties from Iraq. Ann Surg 2007;245:803–811.Google Scholar
3.Ecker, J, Massire, C, Hall, T, et al. Identification of Acinetobacter species and genotyping of Acinetobacter baumannii by multilocus PCR and mass spectrometry. J Clin Micro 2006;44:2921–2932.CrossRefGoogle ScholarPubMed
4.Ecker, DJ, Sampath, R, Blyn, LB, et al. 2005. Rapid identification and strain-typing of respiratory pathogens for epidemic surveillance. Proc Natl Acad Sci US A 2005;102:8012–8017.Google Scholar
5.van Dessel, H, Dijkshoorn, L, van der Reijden, T, et al. Identification of a new geographically widespread multiresistant Acinetobacter baumannii clone from European hospitals. Res Microbiol 2004;155:105–112.CrossRefGoogle ScholarPubMed
6.Urban, C, Segal-Maurer, S, Rahal, J. Considerations in control and treatment of nosocomial infections due to multi-drug resistant Acinetobacter baumannii. Clin Infect Dis 2003;36:1268–1274.Google Scholar
7.Perez, F, Hujer, AM, Hujer, KM, Decker, BK, Rather, PN, Bonomo, RA. Global challenge of multidrug-resistant Acinetobacter baumannii. Antimicrob Agents Chemother 2007;51:3471–3484.CrossRefGoogle Scholar