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Frequency of Disinfectant Resistance Genes in Pediatric Strains of Methicillin-Resistant Staphylococcus aureus

Published online by Cambridge University Press:  02 January 2015

James G. Johnson*
Affiliation:
Department of Medicine, Division of Infectious Diseases, Vanderbilt University School of Medicine, Nashville, Tennessee
Elizabeth J. Save
Affiliation:
Department of Pediatrics, Division of Pediatric Infectious Diseases, Vanderbilt University School of Medicine, Nashville, Tennessee
Natalia Jimenez-Truque
Affiliation:
Department of Pediatrics, Division of Pediatric Infectious Diseases, Vanderbilt University School of Medicine, Nashville, Tennessee
Nicole Soper
Affiliation:
Department of Pediatrics, Division of Pediatric Infectious Diseases, Vanderbilt University School of Medicine, Nashville, Tennessee
Isaac Thomsen
Affiliation:
Department of Pediatrics, Division of Pediatric Infectious Diseases, Vanderbilt University School of Medicine, Nashville, Tennessee
Thomas R. Talbot
Affiliation:
Department of Medicine, Division of Infectious Diseases, Vanderbilt University School of Medicine, Nashville, Tennessee
C. Buddy Creech
Affiliation:
Department of Pediatrics, Division of Pediatric Infectious Diseases, Vanderbilt University School of Medicine, Nashville, Tennessee
*
University Medical Group Infectious Diseases, 890 West Faris Road, Suite 520, Greenville, SC 29605 ([email protected])

Abstract

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Type
Research Briefs
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2013

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References

1.Batra, R, Cooper, BS, Whiteley, C, Patel, AK, Wyncoll, D, Edgeworth, JD. Efficacy and limitation of a chlorhexidine-based decolonization strategy in preventing transmission of methicillin-resistant Staphylococcus aureus in an intensive care unit. Clin Infect Dis 2010;50(2):210217.Google Scholar
2.Lee, AS, Macedo-Vinas, M, Francois, P, et al. Impact of combined low-level mupirocin and genotypic Chlorhexidine resistance on persistent methicillin-resistant Staphylococcus aureus carriage after decolonization therapy: a case-control study. Clin Infect Dis 2011;52(12):14221430.Google Scholar
3.Huang, SS, Septimus, E, Kleinman, K, et al. Targeted versus universal decolonization to prevent ICU infection. N Engl J Med 2013;368(24):22552265.Google Scholar
4.Huet, AA, Raygada, JL, Mendiratta, K, Seo, SM, Kaatz, GW. Multidrug efflux pump overexpression in Staphylococcus aureus after single and multiple in vitro exposures to biocides and dyes. Microbiology 2008;154:31443153.Google Scholar
5.Longtin, J, Seah, C, Siebert, K, et al. Distribution of antiseptic resistance genes qacA, qacB, and smr in methicillin-resistant Staphylococcus aureus isolated in Toronto, Canada, from 2005 to 2009. Antimicrob Agents Chemother 2011;55(6):29993001.CrossRefGoogle Scholar
6.McGann, P, Kwak, YI, Summers, A, Cummings, JF, Waterman, PE, Lesho, EP. Detection of qacA/B in clinical isolates of methicillin-resistant Staphylococcus aureus from a regional healthcare network in the eastern United States. Infect Control Hosp Epidemiol 2011;32(II):11161119.Google Scholar
7.Darouiche, RO, Mansouri, MD, Gawande, PV, Madhyastha, S. Efficacy of combination of Chlorhexidine and protamine sulphate against device-associated pathogens. J Antimicrob Chemother 2008;61(3):651657.Google Scholar
8.Vali, L, Davies, SE, Lai, LL, Dave, J, Amyes, SG. Frequency of biocide resistance genes, antibiotic resistance and the effect of Chlorhexidine exposure on clinical methicillin-resistant Staphylococcus aureus isolates. J Antimicrob Chemother 2008;61(3):524532.Google Scholar
9.McNeil, JC, Hulten, KG, Kaplan, SL, Mahoney, DH, Mason, EO. Staphylococcus aureus infections in pediatric oncology patients: high rates of antimicrobial resistance, antiseptic tolerance and complications. Pediatr Infect Dis J 2013;32(2):124128.Google Scholar