Hostname: page-component-586b7cd67f-dsjbd Total loading time: 0 Render date: 2024-11-29T02:38:11.577Z Has data issue: false hasContentIssue false
  • English
  • Français

The Effectiveness of Routine Daily Chlorhexidine Gluconate Bathing in Reducing Klebsiella pneumoniae Carbapenemase–Producing Enterobacteriaceae Skin Burden among Long-Term Acute Care Hospital Patients

Published online by Cambridge University Press:  10 May 2016

Michael Y. Lin ,
Karen Lolans ,
Donald W. Blom ,
Rosie D. Lyles ,
Shayna Weiner ,
Kavya B. Poluru ,
Nicholas Moore ,
David W. Hines ,
Robert A. Weinstein  and
Mary K. Hayden
...Show all authors
Michael Y. Lin*
Affiliation:
Department of Medicine, Rush University Medical Center, Chicago, Illinois
Karen Lolans
Affiliation:
Department of Pathology, Rush University Medical Center, Chicago, Illinois
Donald W. Blom
Affiliation:
Department of Medicine, Rush University Medical Center, Chicago, Illinois
Rosie D. Lyles
Affiliation:
Department of Medicine, Cook County Health and Hospitals System, Chicago, Illinois
Shayna Weiner
Affiliation:
Department of Medicine, Rush University Medical Center, Chicago, Illinois
Kavya B. Poluru
Affiliation:
Department of Pathology, Rush University Medical Center, Chicago, Illinois
Nicholas Moore
Affiliation:
Department of Pathology, Rush University Medical Center, Chicago, Illinois
David W. Hines
Affiliation:
Metro Infectious Diseases Consultants, Burr Ridge, Illinois
Robert A. Weinstein
Affiliation:
Department of Medicine, Rush University Medical Center, Chicago, Illinois Department of Medicine, Cook County Health and Hospitals System, Chicago, Illinois
Mary K. Hayden
Affiliation:
Department of Medicine, Rush University Medical Center, Chicago, Illinois Department of Pathology, Rush University Medical Center, Chicago, Illinois
*
600 South Paulina Street, Suite 143, Chicago, IL 60612 ([email protected])
Get access Rights & Permissions [Opens in a new window]

Abstract

We evaluated the effectiveness of daily chlorhexidine gluconate (CHG) bathing in decreasing skin carriage of Klebsiella pneumoniae carbapenemase–producing Enterobacteriaceae (KPC) among long-term acute care hospital patients. CHG bathing reduced KPC skin colonization, particularly when CHG skin concentrations greater than or equal to 128 μg/mL were achieved.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 35 , Issue 4: Special Topic Issue: Carbapenem-Resistant Enterobacteriaceae and Multidrug-Resistant Organisms , April 2014 , pp. 440 - 442
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2014

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Centers for Disease Control and Prevention. Vital signs: carbapenem-resistant Enterobacteriaceae. MMWR Morb Mortal Wkly Rep 2013;62:165–170.Google Scholar
2. Lin, MY, Lyles, RD, Lolans, K, et al. The importance of long-term acute care hospitals in the regional epidemiology of Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae. Clin Infect Dis 2013;57:1246–1252.Google Scholar
3. Thurlow, CJ, Prabaker, K, Lin, MY, Lolans, K, Weinstein, RA, Hayden, MK. Anatomic sites of patient colonization and environmental contamination with Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae at long-term acute care hospitals. Infect Control Hosp Epidemiol; 2013;34(1):56–61.Google Scholar
4. Naparstek, L, Carmeli, Y, Chmelnitsky, I, Banin, E, Navon-Venezia, S. Reduced susceptibility to chlorhexidine among extremely-drug-resistant strains of Klebsiella pneumoniae . J Hosp Infect 2012;81(1):15–19.CrossRefGoogle ScholarPubMed
5. McDanel, JS, Murphy, CR, Diekema, DJ, et al. Chlorhexidine and mupirocin susceptibilities of methicillin-resistant staphylococcus aureus from colonized nursing home residents. Antimicrob Agents Chemother 2013;57(1):552–558.CrossRefGoogle ScholarPubMed
6. Edmiston, CE Jr Krepel, CJ, Seabrook, GR, Lewis, BD, Brown, KR, Towne, JB. Preoperative shower revisited: can high topical anti-septic levels be achieved on the skin surface before surgical admission? J Am Coll Surg 2008;207(2):233–239.Google Scholar
7. Clinical and Laboratory Standards Institute (CLSI). Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically; Approved Standard, Eighth Edition. Wayne, PA: CLSI, 2009.Google Scholar
8. Popovich, KJ, Lyles, R, Hayes, R, et al. Relationship between chlorhexidine gluconate skin concentration and microbial density on the skin of critically ill patients bathed daily with chlorhexidine gluconate. Infect Control Hosp Epidemiol 2012;33(9):889–896.Google Scholar
9. Grice, EA, Segre, JA. The skin microbiome. Nat Rev Microbiol 2011;9(4):244–253.Google Scholar