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Does Organic Material on Hospital Surfaces Reduce the Effectiveness of Hypochlorite and UV Radiation for Disinfection of Clostridium difficile?

Published online by Cambridge University Press:  02 January 2015

Andrew Zhang
Affiliation:
Case Western Reserve University School of Medicine, Cleveland, Ohio
Michelle M. Nerandzic
Affiliation:
Research Service, Cleveland Veterans Affairs Medical Center, Cleveland, Ohio
Sirisha Kundrapu
Affiliation:
Case Western Reserve University School of Medicine, Cleveland, Ohio
Curtis J. Donskey*
Affiliation:
Case Western Reserve University School of Medicine, Cleveland, Ohio Geriatric Research Education and Clinical Center, Cleveland Veterans Affairs Medical Center, Cleveland, Ohio
*
Geriatric Research Education and Clinical Center, Cleveland Veterans Affairs Medical Center, 10701 East Boulevard, Cleveland, OH 44106 ([email protected])

Abstract

An organic load of 5%–10% fetal calf serum significantly reduced hypochlorite and UV radiation killing of Clostridium difficile spores, but organic material collected from hospital surfaces did not affect hypochlorite and only modestly affected UV killing of spores. Hypochlorite reduced aerobic microorganisms on unclean surfaces with no wiping.

Type
Concise Communication
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2013

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