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Clinical Experience With Minocycline and Rifampin-Impregnated Central Venous Catheters in Bone Marrow Transplantation Recipients: Efficacy and Low Risk of Developing Staphylococcal Resistance

Published online by Cambridge University Press:  02 January 2015

Ioannis Chatzinikolaou ,
Hend Hanna ,
Linda Graviss ,
Gassan Chaiban ,
Cheryl Perego ,
Rebecca Arbuckle ,
Richard Champlin ,
Rabih Darouiche ,
George Samonis  and
Issam Raad
Ioannis Chatzinikolaou
Affiliation:
Division of Internal Medicine, Department of Infectious Diseases, Infection Control and Employee Health, University of Texas, M. D. Anderson Cancer Center, Houston, Texas Division of Internal Medicine, Department of Infectious Diseases, School of Medicine, University of Crete, Greece
Hend Hanna*
Affiliation:
Division of Internal Medicine, Department of Infectious Diseases, Infection Control and Employee Health, University of Texas, M. D. Anderson Cancer Center, Houston, Texas
Linda Graviss
Affiliation:
Division of Internal Medicine, Department of Infectious Diseases, Infection Control and Employee Health, University of Texas, M. D. Anderson Cancer Center, Houston, Texas
Gassan Chaiban
Affiliation:
Division of Internal Medicine, Department of Infectious Diseases, Infection Control and Employee Health, University of Texas, M. D. Anderson Cancer Center, Houston, Texas
Cheryl Perego
Affiliation:
Division of Internal Medicine, Department of Infectious Diseases, Infection Control and Employee Health, University of Texas, M. D. Anderson Cancer Center, Houston, Texas
Rebecca Arbuckle
Affiliation:
Division of Pharmacy, University of Texas, M. D. Anderson Cancer Center, Houston, Texas
Richard Champlin
Affiliation:
Department of Bone Marrow Transplantation, University of Texas, M. D. Anderson Cancer Center, Houston, Texas
Rabih Darouiche
Affiliation:
Section of Infectious Diseases, VA Medical Center and Baylor College of Medicine, Houston, Texas
George Samonis
Affiliation:
Division of Internal Medicine, Department of Infectious Diseases, School of Medicine, University of Crete, Greece
Issam Raad
Affiliation:
Division of Internal Medicine, Department of Infectious Diseases, Infection Control and Employee Health, University of Texas, M. D. Anderson Cancer Center, Houston, Texas
*
Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas, M. D. Anderson Cancer Center, 1515 Holcombe Boulevard (Unit 402), Houston, TX 77030
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Abstract

In this retrospective evaluation of the 4-year clinical use of minocycline and rifampin-impregnated catheters in bone marrow transplantation (BMT) patients, we report low risk of development of staphylococcal resistance to the antibiotics coating the catheters and efficacy in preventing primary staphylococcal bloodstream infections.

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 24 , Issue 12 , December 2003 , pp. 961 - 963
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2003 

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References

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