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A Chryseobacterium meningosepticum Outbreak in a Neonatal Ward

Published online by Cambridge University Press:  02 January 2015

Serdal Güngör ,
Metehan Özen ,
Aysehan Akinci  and
Riza Durmaz
Serdal Güngör
Affiliation:
Department of Pediatrics, Medical Faculty of Inönü University, Malatya, Turkey
Metehan Özen*
Affiliation:
Department of Pediatrics, Medical Faculty of Inönü University, Malatya, Turkey
Aysehan Akinci
Affiliation:
Division of Pediatric Endocrinology, Department of Pediatrics, Medical Faculty of Inönü University, Malatya, Turkey
Riza Durmaz
Affiliation:
Department of Clinical Microbiology, Turgut Özal Research Center, Medical Faculty of Inönü University, Malatya, Turkey
*
Uran Kent, E-2 Blok, Daire: 26, Demetevler, Ankara, Turkey
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Abstract

Objective:

To report epidemiologic, bacteriologic, and clinical features of a Chryseobacterium meningosepticum outbreak.

Design:

Outbreak investigation.

Setting:

A neonatal intensive care unit (NICU) of a referral teaching hospital.

Methods:

During 2 weeks in September 2001, four neonates in the NICU developed sepsis and underwent laboratory investigation. Multiple samples were obtained for cultures from endotracheal tubes, mechanical ventilators and humidifier boxes, infant incubators, parenteral and antiseptic solutions, feeding bottles, sinks, faucets, doors, and healthcare workers.

Results:

C. meningosepticum was isolated from the blood cultures of four patients. The first isolate was identified 5 days after the death of the index case. Although all isolates were ciprofloxacin susceptible in vitro, the remaining three patients did not respond to ciprofloxacin therapy given for 6 or 7 days. Therapy was switched to vancomycin and rifampin and all three patients survived, with one having a complication (hydrocephalus). Environmental surveillance revealed C. meningosepticum in the stock lipid solution as the source of the epidemic. The outbreak was controlled after discontinuation of intravenous lipid solution, restriction of further neonatal admissions, and thorough disinfection of the unit and its equipment.

Conclusion:

Early identification of an epidemic and its source is important in avoiding morbidity and mortality. A contaminated lipid stock bottle was the source of this outbreak associated with multiple cases and one death.

Type
Original Articles
Information
Infection Control & Hospital Epidemiology , Volume 24 , Issue 8 , August 2003 , pp. 613 - 617
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2003

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