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Central Line–Associated Bloodstream Infections in Adult Hematology Patients with Febrile Neutropenia An Evaluation of Surveillance Definitions Using Differential Time to Blood Culture Positivity

Published online by Cambridge University Press:  02 January 2015

Joshua T. Freeman*
Affiliation:
Department of Clinical Microbiology, Auckland District Healthboard, Auckland, New Zealand
Anna Elinder-Camburn
Affiliation:
Department of Haematology, Auckland District Healthboard, Auckland, New Zealand
Catherine McClymont
Affiliation:
Department of Infection Prevention and Control, Auckland District Healthboard, Auckland, New Zealand
Deverick J. Anderson
Affiliation:
Division of Infectious Diseases, Duke University Medical Center, Durham, North Carolina
Mary Bilkey
Affiliation:
Department of Clinical Microbiology, Auckland District Healthboard, Auckland, New Zealand
Deborah A. Williamson
Affiliation:
Department of Clinical Microbiology, Auckland District Healthboard, Auckland, New Zealand
Leanne Berkahn
Affiliation:
Department of Haematology, Auckland District Healthboard, Auckland, New Zealand
Sally A. Roberts
Affiliation:
Department of Clinical Microbiology, Auckland District Healthboard, Auckland, New Zealand
*
Clinical Microbiologist, Auckland District Healthboard, LabPlus, 2 Grafton Road, Auckland, New Zealand ([email protected])

Abstract

We used differential time to positivity between central and peripheral blood cultures to evaluate the positive predictive value (PPV) of the National Healthcare Safety Network central line–associated bloodstream infection (CLABSI) surveillance definition among hematology patients with febrile neutropenia. The PPV was 27.7%, which suggests that, when the definition is applied to this population, CLABSI rates will be substantially overestimated.

Type
Concise Communication
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2013

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