Hostname: page-component-586b7cd67f-2brh9 Total loading time: 0 Render date: 2024-11-30T20:15:09.623Z Has data issue: false hasContentIssue false

Case-Control Study of Risk Factors for Mediastinitis After Cardiovascular Surgery

Published online by Cambridge University Press:  21 June 2016

M. J. López Gude
Affiliation:
Department of Cardiothoracic Surgery, University Hospital “12 de Octubre”, Madrid, Spain
R. San Juan*
Affiliation:
Unit of Infectious Diseases, University Hospital “12 de Octubre”, Madrid, Spain
J. M. Aguado
Affiliation:
Unit of Infectious Diseases, University Hospital “12 de Octubre”, Madrid, Spain
L. Maroto
Affiliation:
Department of Cardiothoracic Surgery, University Hospital “12 de Octubre”, Madrid, Spain
F. López-Medrano
Affiliation:
Unit of Infectious Diseases, University Hospital “12 de Octubre”, Madrid, Spain
J. M. Cortina Romero
Affiliation:
Department of Cardiothoracic Surgery, University Hospital “12 de Octubre”, Madrid, Spain
J. J. Rufilanchas
Affiliation:
Department of Cardiothoracic Surgery, University Hospital “12 de Octubre”, Madrid, Spain
*
Unidad de Enfermedades Infecciosas, Hospital Universitario 12 de Octubre, Edificio Maternidad, planta 6°, Avenida de Andalucía km 5, 400, 28041 Madrid, Spain ([email protected])

Abstract

We report results of a case-control study in which we evaluated 41 risk factors potentially associated with the development of post-surgical mediastinitis. There were 163 case patients and 326 control patients. Independent risk factors kept in the final multivariate logistic regression model were obesity (defined as a body mass index of greater than 30), diabetes mellitus, chronic obstructive pulmonary disease, preoperative stay longer than 1 week, pulmonary hypertension, perioperative myocardial infarction, and reoperation.

Type
Concise Communications
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2006

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Munoz, P, Menasalvas, A, Bernaldo de Quiros, JC, Desco, M, Vallejo, JL, Bouza, E. Postsurgical mediastinitis: a case-control study. Clin Infect Dis 1997; 25:10601064.CrossRefGoogle ScholarPubMed
2. Bitkover, CY, Gardlund, B. Mediastinitis after cardiovascular operations: a case-control study of risk factors. Ann Thorac Surg 1998; 65:3640.CrossRefGoogle ScholarPubMed
3. Abboud, CS, Wey, SB, Baltar, VT. Risk factors for mediastinitis after cardiac surgery. Ann Thorac Surg 2004; 77:676683.CrossRefGoogle ScholarPubMed
4. Garner, JS, Jarvis, WR, Emori, TG, Horan, TC, Hughes, JM. CDC definitions for nosocomial infections, 1988. Am J Infect Control 1988; 16:128140.Google Scholar
5. Russo, PL, Spelman, DW. A new surgical-site infection risk index using risk factors identified by multivariate analysis for patients undergoing coronary artery bypass graft surgery. Infect Control Hosp Epidemiol 2002; 23:372376.Google Scholar
6. Olsen, MA, Lock-Buckley, P, Hopkins, D, Polish, LB, Sundt, TM, Fraser, VJ. The risk factors for deep and superficial chest surgical-site infections after coronary artery bypass graft surgery are different. J Thorac Cardiovasc Surg 2002; 124:136145.CrossRefGoogle ScholarPubMed
7. Losanoff, JE, Richman, BW, Jones, JW. Risk analysis of deep sternal wound infection and mediastinitis in cardiac surgery. Thorac Cardiovasc Surg 2002; 50:385.CrossRefGoogle ScholarPubMed
8. Gummert, JF, Barten, MJ, Hans, C, et al. Mediastinitis and cardiac surgery—an updated risk factor analysis in 10,373 consecutive adult patients. Thorac Cardiovasc Surg 2002; 50:8791.CrossRefGoogle Scholar
9. Trick, WE, Scheckler, WE, Tokars, JI, et al. Modifiable risk factors associated with deep sternal site infection after coronary artery bypass grafting. J Thorac Cardiovasc Surg 2000; 119:108114.Google Scholar
10. Ottino, G, De Paulis, R, Pansini, S, et al. Major sternal wound infection after open-heart surgery: a multivariate analysis of risk factors in 2,579 consecutive operative procedures. Ann Thorac Surg 1987; 44:173179.Google Scholar
11. Grossi, EA, Culliford, AT, Krieger, KH, et al. A survey of 77 major infectious complications of median sternotomy: a review of 7,949 consecutive operative procedures. Ann Thorac Surg 1985; 40:214223.Google Scholar