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Surveillance Cultures for Detection of Methicillin-Resistant Staphylococcus aureus: Diagnostic Yield of Anatomic Sites and Comparison of Provider- and Patient-Collected Samples

Published online by Cambridge University Press:  02 January 2015

Ebbing Lautenbach ,
Irving Nachamkin ,
Baofeng Hu ,
Neil O. Fishman ,
Pam Tolomeo ,
Priya Prasad ,
Warren B. Bilker  and
Theoklis E. Zaoutis
Ebbing Lautenbach*
Affiliation:
Division of Infectious Diseases of the Department of Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania Department of Biostatistics and Epidemiology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania Center for Clinical Epidemiology and Biostatistics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania Center for Education and Research on Therapeutics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Irving Nachamkin
Affiliation:
Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Baofeng Hu
Affiliation:
Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania Center for Clinical Epidemiology and Biostatistics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Neil O. Fishman
Affiliation:
Division of Infectious Diseases of the Department of Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania Center for Education and Research on Therapeutics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Pam Tolomeo
Affiliation:
Center for Clinical Epidemiology and Biostatistics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Priya Prasad
Affiliation:
University of Pennsylvania School of Medicine, and Division of Infectious Diseases, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Warren B. Bilker
Affiliation:
Department of Biostatistics and Epidemiology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania Center for Clinical Epidemiology and Biostatistics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania Center for Education and Research on Therapeutics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Theoklis E. Zaoutis
Affiliation:
Department of Biostatistics and Epidemiology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania Center for Clinical Epidemiology and Biostatistics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania Center for Education and Research on Therapeutics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania University of Pennsylvania School of Medicine, and Division of Infectious Diseases, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
*
University of Pennsylvania School of Medicine, Center for Clinical Epidemiology and Biostatistics, 825 Blockley Hall, 423 Guardian Dr., Philadelphia, PA 19104-6021 ([email protected])
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Abstract

We studied provider- and patient-collected samples from multiple anatomic sites to determine the yield for detection of methicillin-resistant Staphylococcus aureus (MRSA). Sampling of multiple sites was required to achieve a sensitivity of more than 90% for MRSA colonization. Groin and perineum samples yielded positive results significantly more often for community-onset MRSA than for hospital-onset MRSA. Agreement rates between provider- and patient-collected swab specimens were excellent.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 30 , Issue 4 , April 2009 , pp. 380 - 382
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2009

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References

1.Fridkin, SK, Hageman, JC, Morrison, MS, et al.Methicillin-resistant Staphylococcus aureus disease in three communities. N Engl J Med 2005;352:1436–1444.CrossRefGoogle ScholarPubMed
2.Kluytmans, J, van Belkum, A, Verbrugh, H. Nasal carriage of Staphylococcus aureus: epidemiology, underlying mechanisms, and associated risks. Clin Microbiol Rev 1997;10:505–520.CrossRefGoogle ScholarPubMed
3.Graham, PL, Lin, SX, Larson, EL. A US population-based survey of Staphylococcus aureus colonization. Ann Intern Med 2006;144:318–325.CrossRefGoogle ScholarPubMed
4.Grmek-Kosnik, I, Ihan, A, Dermota, U, Rems, M, Kosnik, M, Jorn Kolmos, H. Evaluation of separate vs pooled swab cultures, different media, broth enrichment and anatomical sites of screening for the detection of methicillin-resistant Staphylococcus aureus from clinical specimens. J Hosp Infect 2005;61:155–161.CrossRefGoogle ScholarPubMed
5.Bishop, EJ, Grabsch, EA, Ballard, SA, et al.Concurrent analysis of nose and groin swab specimens by the IDI-MRSA PCR assay is comparable to analysis by individual-specimen PCR and routine culture assays for detection of colonization by methicillin-resistant Staphylococcus aureus. J Clin Microbiol 2006;44:2904–2908.CrossRefGoogle ScholarPubMed
6.Coello, R, Jimenez, J, Garcia, M, et al.Prospective study of infection, colonization and carriage of methicillin-resistant Staphylococcus aureus in an outbreak affecting 990 patients. Eur J Clin Microbiol Infect Dis 1994;13:74–81.CrossRefGoogle Scholar
7.Ringberg, H, Cathrine Petersson, A, Walder, M, Hugo Johansson, PJ. The throat: an important site for MRSA colonization. Scand J Infect Dis 2006;38:888–893.CrossRefGoogle ScholarPubMed
8.Han, Z, Lautenbach, E, Fishman, NO, Nachamkin, I. Evaluation of Mannitol Salt Agar, CHROMagar Staph aureus and CHROMagar MRSA for detection of methicillin-resistant Staphylococcus aureus from nasal swab specimens. J Med Microbiol 2007;56:43–46.CrossRefGoogle ScholarPubMed
9.Meurman, O, Routamaa, M, Peltonen, R. Screening for methicillin-resistant Staphylococcus aureus: which anatomical sites to culture? J Hosp Infect 2005;61:351–353.CrossRefGoogle ScholarPubMed
methicillin-resistant Staphylococcus aureus caused by a new phage-type (EMRSA-16). J Hosp Infect 1995;29:87–106.CrossRefGoogle Scholar