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Risk of SARS-CoV-2 infection in hospitalized patients following SARS-CoV-2 exposures before and during hospitalization

Published online by Cambridge University Press:  04 October 2024

Selina Ehrenzeller
Affiliation:
Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, USA Department of Medicine, Brigham and Women’s Hospital, Boston, USA Department of Medicine, Limmattal Hospital Zurich, Schlieren, Switzerland
Anna Agan
Affiliation:
Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, USA
Chanu Rhee
Affiliation:
Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, USA Department of Medicine, Brigham and Women’s Hospital, Boston, USA
Michael Klompas*
Affiliation:
Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, USA Department of Medicine, Brigham and Women’s Hospital, Boston, USA
*
Corresponding author: Michael Klompas; Email: [email protected]

Abstract

Little is known regarding SARS-CoV-2 infection risk following SARS-CoV-2 exposures in hospitalized patients. Amongst 11,997 patients in 14 hospitals exposed 2020–2023, 6.5% tested positive (median 3d after exposure). Positivity rates were 6.7% vs 5.8% for Omicron vs pre-Omicron exposures (P = 0.07) and 7.6% vs 4.6% for exposures before vs after admission (P < 0.001).

Type
Concise Communication
Copyright
© The Author(s), 2024. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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