Hostname: page-component-78c5997874-g7gxr Total loading time: 0 Render date: 2024-11-02T21:07:00.730Z Has data issue: false hasContentIssue false
  • English
  • Français

Reality Check: Should We Use Vancomycin for the Prophylaxis of Intravascular Catheter-Associated Infections?

Published online by Cambridge University Press:  02 January 2015

Lisa A. Grohskopf ,
Dennis G. Maki ,
Annette H. Sohn ,
Ronda L. Sinkowitz-Cochran ,
William R. Jarvis  and
Donald A. Goldmann
Lisa A. Grohskopf*
Affiliation:
Hospital Infections Program, Division of Applied Public Health Training, Epidemiology Program Office, Centers for Disease Control and Prevention, Public Health Service, United States Department of Health and Human Services, Atlanta, Georgia National Center for Infectious Diseases; Epidemic Intelligence Service, Division of Applied Public Health Training, Epidemiology Program Office, Centers for Disease Control and Prevention, Public Health Service, United States Department of Health and Human Services, Atlanta, Georgia
Dennis G. Maki
Affiliation:
Infectious Diseases Section, Department of Medicine, University of Wisconsin Hospital and Clinics, Madison, Wisconsin
Annette H. Sohn
Affiliation:
Hospital Infections Program, Division of Applied Public Health Training, Epidemiology Program Office, Centers for Disease Control and Prevention, Public Health Service, United States Department of Health and Human Services, Atlanta, Georgia National Center for Infectious Diseases; Epidemic Intelligence Service, Division of Applied Public Health Training, Epidemiology Program Office, Centers for Disease Control and Prevention, Public Health Service, United States Department of Health and Human Services, Atlanta, Georgia
Ronda L. Sinkowitz-Cochran
Affiliation:
Hospital Infections Program, Division of Applied Public Health Training, Epidemiology Program Office, Centers for Disease Control and Prevention, Public Health Service, United States Department of Health and Human Services, Atlanta, Georgia
William R. Jarvis
Affiliation:
Hospital Infections Program, Division of Applied Public Health Training, Epidemiology Program Office, Centers for Disease Control and Prevention, Public Health Service, United States Department of Health and Human Services, Atlanta, Georgia
Donald A. Goldmann
Affiliation:
Infection Control Program and Department of Medicine, Children's Hospital, Boston, Massachusetts
*
Hospital Infections Program, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Mailstop E-69, Atlanta, GA 30333
Get access Rights & Permissions [Opens in a new window]

Abstract

The use of intravascular catheters is associated with increased risk of bloodstream infections, principally caused by coagulase-negative staphylococci. This “Reality Check” session, held at die 4th Decennial International Conference on Nosocomial and Healthcare-Associated Infections, focused on the question of whether, and in what manner, vancomycin should be used for the prophylaxis of these infections.

Type
From the 4th Decennial International Conference
Information
Infection Control & Hospital Epidemiology , Volume 22 , Issue 3 , March 2001 , pp. 176 - 179
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2001

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Maki, DG. Infections caused by intravascular devices used for infusion therapy: pathogenesis, prevention, and management. In: Bisno, AL, Waldvogel, FA, eds. Infections Associated With Indwelling Medical Devices. 2nd ed. Washington, DC: American Society for Microbiology;1994:155–211.Google Scholar
2. Pittet, D, Tarara, D, Wenzel, RP. Nosocomial bloodstream infection in critically ill patients: excess length of stay, extra costs, and attributable mortality. JAMA 1994;271:1598–1601.Google Scholar
3. Centers for Disease Control and Prevention. Recommendations for preventing the spread of vancomycin resistance. Recommendations of the Hospital Infection Control Practices Advisory Committee (HICPAC). MMWR 1995;44(RR-12):1–13.Google Scholar
4. Banerjee, SN, Emori, TG, Culver, DH, Gaynes, RP, Jarvis, WR, Horan, T, et al. Secular trends in nosocomial primary bloodstream infection in the United States, 1980-1989. National Nosocomial Infections Surveillance System. Am J Med 1991;91(suppl 3B):86S–89S.Google Scholar
5. Freeman, J, Epstein, MF, Smith, NE, Platt, R, Sidebottom, DG, Goldmann, DA. Extra hospital stay and antibiotic usage with nosocomial coagulase-negative staphylococcal bacteremia in two neonatal intensive care unit populations. Am J Dis Child 1990;144:324–329.Google Scholar
6. Huebner, J, Goldmann, DA. Coagulase-negative staphylococci: role as pathogens. Annu Rev Med 1999;50:223–236.CrossRefGoogle ScholarPubMed
7. Mermel, LA. Prevention of catheter-related infections. Ann Intern Med 2000;132:391–402.CrossRefGoogle ScholarPubMed
8. Vassilomanolakis, M, Plataniotis, G, Koumakis, G, Hajichristou, H, Skouteri, H, Dova, H, et al. Central venous catheter-related infections after bone marrow transplantation in patients with malignancies: a prospective study with short-course vancomycin prophylaxis. Bone Marrow Transplant 1995;15:77–80.Google Scholar
9. Spafford, PS, Sinkin, RA, Cox, C, Reubens, L, Powell, KR. Prevention of central venous catheter-related coagulase-negative staphylococcal sepsis in neonates. J Pediatr 1994;125:259–263.CrossRefGoogle ScholarPubMed
10. Schwartz, C, Henrickson, KJ, Roghmann, K, Powell, K. Prevention of bacteremia attributed to luminal colonization of tunneled central venous catheters with vancomycin-susceptible organisms. J Clin Oncol 1990;8:1591–1597.Google Scholar
11. Carratala, J, Niubo, J, Fernandez-Sevilla, A, Juve, E, Castellsague, X, Berlanga, J, et al. Randomized, double-blind trial of an antibiotic-lock technique for prevention of gram-positive central venous catheter-related infection in neutropenic patients with cancer. Antimicrob Agents Chemother 1999;43:2200–2204.Google Scholar
12. Barriga, FJ, Varas, M, Potin, M, Sapunar, F, Rojo, H, Martinez, A, et al. Efficacy of a vancomycin solution to prevent bacteremia associated with an indwelling central venous catheter in neutropenic and non-neutropenic cancer patients. Med Pediatr Oncol 1997;28:196–200.Google Scholar
13. Henrickson, KJ, Axtell, RA, Hoover, SM, Kuhn, SM, Pritchett, J, Kehl, SC, et al. Prevention of central venous catheter-related infections and thrombotic events in immunocompromised children by the use of a vancomycin/ciprofloxacin/heparin flush solution: a randomized, multicenter, double-blind trial. J Clin Oncol 2000;18:1269–1278.Google Scholar
14. Maki, DG, Ringer, M, Alvarado, CJ. Prospective randomized trial of povidone-iodine, alcohol, and chlorhexidine for prevention of infection associated with central venous and arterial catheters. Lancet 1991;338:339–343.Google Scholar
15. Raad, II, Hohn, DC, Gilbreath, BJ, Suleiman, N, Hill, LA, Bruso, PA, et al. Prevention of central venous catheter-related infections by using maximal sterile barrier precautions during insertion. Infect Control Hosp Epidemiol 1994;15:231–238.Google Scholar
16. Cobb, DK, High, KP, Sawyer, RG, Sable, CA, Adams, RB, Lindley, DA, et al. A controlled trial of scheduled replacement of central venous and pulmonary artery catheters. N Engl J Med 1992;327:1062–1068.Google Scholar
17. Maki, DG, Cobb, L, Garman, JK, Shapiro, JM, Ringer, M, Helgerson, RB. An attachable silver-impregnated cuff for prevention of infection with central venous catheters: a prospective randomized multicenter trial. Am J Med 1988;85:307–314.Google Scholar
18. Maki, DG, Stolz, SM, Wheeler, S, Mermel, LA. Prevention of central venous catheter-related bloodstream infection by use of an antiseptic-impregnated catheter. A randomized, controlled trial. Ann Intern Med 1997;127:257–266.Google Scholar
19. Raad, I, Darouiche, R, Dupuis, J, Abi-Said, D, Gabrielli, A, Hachem, R, et al. Central venous catheters coated with minocycline and rifampin for the prevention of catheter-related colonization and bloodstream infections: a randomized, double-blind trial. Ann Intern Med 1997;127:267–274.Google Scholar
20. Maki, DG, Narans, LL, Knasinski, V, Kluger, D. Prospective, randomized, investigator-masked study of a novel chlorhexidine-impregnated disk on central venous and arterial catheters. Presented at the 4th Decennial International Conference on Nosocomial and Healthcare-Associated Infections; March 2000; Atlanta, Georgia. Abstract.Google Scholar
21. Freeman, J, Goldmann, DA, Smith, NE, Sidebottom, DG, Epstein, MF, Platt, R. Association of intravenous lipid emulsion and coagulase-negative staphylococcal bacteremia in neonatal intensive care units. N Engl J Med 1990;323:301–308.Google Scholar
22. Inoue, Y, Nezu, R, Matsuda, H, Fujii, M, Nakai, S, Wasa, M, et al. Prevention of catheter-related sepsis during parenteral nutrition: effect of a new connection device. J Parenter Enteral Nutr 1992;16:581–585.Google Scholar
23. Segura, M, Alvarez-Lerma, F, Tellado, JM, Jimenez-Ferreres, J, Oms, L, Rello, J, et al. A clinical trial on the prevention of catheter-related sepsis using a new hub model. Ann Surg 1996;223:363–369.Google Scholar
24. Sherertz, RJ, Ely, EW, Westbrook, DM, Gledhill, KS, Steed, SA, Kiger, B, et al. Education of physicians-in-training can decrease the risk for vascular catheter infection. Ann Intern Med 2000;132:641–648.Google Scholar