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The Prediction of Complicated Clostridium difficile Infections in Children

Published online by Cambridge University Press:  10 May 2016

Sarah Tschudin-Sutter ,
Pranita D. Tamma ,
Aaron M. Milstone  and
Trish M. Perl
Sarah Tschudin-Sutter*
Affiliation:
Department of Medicine, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland
Pranita D. Tamma
Affiliation:
Department of Pediatrics, Division of Pediatric Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland
Aaron M. Milstone
Affiliation:
Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland Department of Pediatrics, Division of Pediatric Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland
Trish M. Perl
Affiliation:
Department of Medicine, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland
*
Department of Medicine, Division of Infectious Diseases, 327 A Billings Building, Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MD 21287 ([email protected]).
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Extract

We validated proposed definitions for severe Clostridium difficile infection (CDI) in adults for prediction of complicated CDI in children. Complicated CDI occurred in 9 of 202 cases. Definitions for severe CDI in adults showed poor measures for discrimination of complicated CDI in children, which calls into question the usefulness of such definitions in pediatric cohorts.

Infect Control Hosp Epidemiol 2014;35(7):901–903

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 35 , Issue 7 , July 2014 , pp. 901 - 903
Copyright
© 2014 by The Society for Healthcare Epidemiology of America. All rights reserved.

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