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Intravascular Catheter Colonization and Related Bloodstream Infection in Critically III Neonates

Published online by Cambridge University Press:  21 June 2016

Wendy A. Cronin ,
Teresa P. Germanson  and
Leigh G. Donowitz
Wendy A. Cronin
Affiliation:
Department of Internal Medicine, Hospital Epidemiology, the University of Virginia Health Sciences Center, Charlottesville, Virginia
Teresa P. Germanson
Affiliation:
Department of Neurosurgery, the University of Virginia Health Sciences Center, Charlottesville, Virginia
Leigh G. Donowitz*
Affiliation:
Department of Pediatrics, the University of Virginia Health Sciences Center, Charlottesville, Virginia
*
Department of Pediatrics, Box 386, University of Virginia, Health Sciences Center, Charlottesville, VA 22908
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Abstract

Intravascular catheter tip colonization was prospectively evaluated in critically ill neonates to determine its relationship to the type of device used, duration of catheterization, insertion site and nosocomial bloodstream infection. Sixty-one percent (376 of 621) of all intravascular catheter tips were retrieved from 91 infants. Thirteen percent (41 of 310) of peripheral intravenous, 14% (6 of 42) of umbilical, 21% (3 of 11) of central venous, 36% (4 of 11) of peripheral arterial and 100% (2 of 2) of femoral catheters were colonized. Duration of catheterization was significantly longer for colonized lines (p < .001). Eight of 26 (30.8%) peripheral intravenous catheters remaining in place for more than three days were colonized, compared with 33 of 284 (11.6%) at three days or less (p = 0.012). Coagulase-negative staphylococcus was the organism most frequently isolated from catheter tips and bloodstream infections. Catheter colonization rates in this population were higher than those found in adults. Heavily manipulated devices and those in place for longer periods of time were the most frequently colonized.

Type
Original Articles
Information
Infection Control & Hospital Epidemiology , Volume 11 , Issue 6 , June 1990 , pp. 301 - 308
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1990

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