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Infection Control in Gene Therapy

Published online by Cambridge University Press:  02 January 2015

Martin E. Evans  and
Judith A. Lesnaw
Martin E. Evans*
Affiliation:
University of Kentucky Medical Center, T.H. Morgan School of Biological Sciences, University of Kentucky, Lexington, Kentucky
Judith A. Lesnaw
Affiliation:
Division of Molecular and Cell Biology, T.H. Morgan School of Biological Sciences, University of Kentucky, Lexington, Kentucky
*
HG608 UKMC, 800 Rose St, Lexington, KY 40536-0293
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Abstract

Gene therapy is now being studied for the treatment of a wide variety of acquired and inherited diseases. Viruses used as vectors for gene transfer include retroviruses, adenoviruses, vaccinia viruses, adeno-associated viruses, and herpesviruses. These vectors, developed in the laboratory and in animal studies, are now being introduced into the clinical arena. Infection control practitioners will be involved invariably in reviewing the use of these agents in their clinics and hospitals. This review summarizes key aspects of the more common vectors and makes recommendations for infection control.

Type
Emerging Infectious Diseases
Information
Infection Control & Hospital Epidemiology , Volume 20 , Issue 8 , August 1999 , pp. 568 - 576
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1999

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