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Effect of Screening for Methicillin-Resistant Staphylococcus aureus Carriage by Polymerase Chain Reaction on the Duration of Unnecessary Preemptive Contact Isolation

Published online by Cambridge University Press:  02 January 2015

Ilker Uçkay ,
Hugo Sax ,
Anne Iten ,
Véronique Camus ,
Gesuele Renzi ,
Jacques Schrenzel ,
Arnaud Perrier  and
Didier Pittet
Ilker Uçkay
Affiliation:
Infection Control Program, University of Geneva Hospitals and Faculty of Medicine, Geneva, Switzerland
Anne Iten
Affiliation:
Service of General Internal Medicine, University of Geneva Hospitals and Faculty of Medicine, Geneva, Switzerland
Véronique Camus
Affiliation:
Infection Control Program, University of Geneva Hospitals and Faculty of Medicine, Geneva, Switzerland
Gesuele Renzi
Affiliation:
Central Laboratory of Bacteriology, University of Geneva Hospitals and Faculty of Medicine, Geneva, Switzerland
Jacques Schrenzel
Affiliation:
Central Laboratory of Bacteriology, University of Geneva Hospitals and Faculty of Medicine, Geneva, Switzerland
Arnaud Perrier
Affiliation:
Service of General Internal Medicine, University of Geneva Hospitals and Faculty of Medicine, Geneva, Switzerland
Didier Pittet*
Affiliation:
Infection Control Program, University of Geneva Hospitals and Faculty of Medicine, Geneva, Switzerland
*
Infection Control Program, University of Geneva Hospitals and Facuty of Medicine, 24 Rue Micheli-du-Crest 1211, Geneva 14, Switzerland ([email protected])
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Abstract

A high prevalence of methicillin-resistant Staphylococcus aureus (MRSA) carriage at hospital readmission among previous MRSA carriers warrants screening and preemptive isolation precautions. The replacement of culture on chromogenic agar with rapid quantitative polymerase chain reaction for readmission screening reduces the number of unnecessary preemptive isolation-days by 54% (from 6.88 to 3.14 isolation-days) and related costs by 45% (from US$113.2 to US$62.1) for patients who test negative for MRSA.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 29 , Issue 11 , November 2008 , pp. 1077 - 1079
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2008

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References

1.Cosgrove, SE, Qi, Y, Kaye, KS, et al.The impact of methicillin resistance in Staphylococcus aureus bacteremia on patient outcomes: mortality, length of stay, and hospital charges. Infect Control Hosp Epidemiol 2005;26:166–174.Google Scholar
2.Siegel, JD, Rhinehart, E, Jackson, M, Chiarello, L; Healthcare Infection Control Practices Advisory Committee. Management of multidrug-resistant organisms in healthcare settings, 2006. Available at: http://www.cdc.gov/ncidod/dhqp/pdf/ar/mdroguideline2006.pdf. Accessed January 10, 2008.CrossRefGoogle Scholar
3.Harbarth, S, Sax, H, Fankhauser-Rodriguez, C, Schrenzel, J, Agostinho, A, Pittet, D. Control of a cluster of community-associated, methicillin-resistant Staphylococcus aureus in neonatology. J Hosp Infect 2006;63:93–100.Google Scholar
4.Pittet, D, Safran, E, Harbarth, S, et al.Automatic alerts for methicillin-resistant Staphylococcus aureus surveillance and control: role of a hospital information system. Infect Control Hosp Epidemiol 1996;17:496–502.CrossRefGoogle ScholarPubMed
5.Rubinovitch, B, Pittet, D. Screening for methicillin-resistant Staphylococcus aureus in the endemic hospital: what have we learned? J Hosp Infect 2001;47:9–18.CrossRefGoogle ScholarPubMed
6.François, P, Pittet, D, Bento, M, et al.Rapid detection of methicillin-resistant Staphylococcus aureus directly from sterile or nonsterile clinical samples by a new molecular assay. J Clin Microbiol 2003;41:254–260.CrossRefGoogle ScholarPubMed
7.Harbarth, S, Masuet-Aumatell, C, Schrenzel, J, et al.Evaluation of rapid screening and pre-emptive contact isolation for detecting and controlling methicillin-resistant Staphylococcus aureus in critical care: an interventional cohort study. Crit Care 2006;10:R25.CrossRefGoogle ScholarPubMed
8.Cunningham, R, Jenks, P, Northwood, J, et al.Effect on MRSA transmission of rapid PCR testing of patients admitted to critical care. I Hosp Infect 2007;65:24–8.CrossRefGoogle ScholarPubMed
9.Karchmer, TB, Durbin, LJ, Simonton, BM, Farr, BM. Cost-effectiveness of active surveillance cultures and contact/droplet precautions for control of methicillin-resistant Staphykcoccus aureus. J Hosp Infect 2002;51:126–132.CrossRefGoogle ScholarPubMed
10.Wagenvoort, JH, van de Cruijs, MF, Meuwissen, CT, et al.Comparison of an enrichment broth-enhanced commercial PCR procedure versus bacteriological culture for separating non-colonized from suspected or colonized MRSA individuals. Eur J Clin Microbiol Infect Dis 2007;26:155–160.CrossRefGoogle ScholarPubMed