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Discontinuation of Reflex Testing of Stool Samples for Vancomycin-Resistant Enterococci Resulted in Increased Prevalence

Published online by Cambridge University Press:  02 January 2015

Mandy Bodily ,
Kathleen M. McMullen ,
Anthony J. Russo ,
Nupur D. Kittur ,
Joan Hoppe-Bauer  and
David K. Warren
Mandy Bodily*
Affiliation:
Barnes-Jewish Hospital, Infection Prevention Department, Saint Louis, Missouri
Kathleen M. McMullen
Affiliation:
Barnes-Jewish Hospital, Infection Prevention Department, Saint Louis, Missouri
Anthony J. Russo
Affiliation:
Barnes-Jewish Hospital, Infection Prevention Department, Saint Louis, Missouri
Nupur D. Kittur
Affiliation:
Washington University in Saint Louis, Infectious Diseases, Saint Louis, Missouri
Joan Hoppe-Bauer
Affiliation:
Barnes-Jewish Hospital, Microbiology Laboratory, Saint Louis, Missouri
David K. Warren
Affiliation:
Washington University in Saint Louis, Infectious Diseases, Saint Louis, Missouri
*
8451 Pearl Street, Denver, CO 80229 ([email protected])
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Abstract

Discontinuation of reflex testing of stool submitted for Clostridium difficile testing for vancomycin-resistant enterococci (VRE) led to an increase in the number of patients with healthcare-associated VRE bacteremia and bacteriuria (0.21 vs 0.36 cases per 1,000 patient-days; P < .01). Cost-benefit analysis showed reflex screening and isolation of VRE reduced hospital costs.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 34 , Issue 8 , August 2013 , pp. 838 - 840
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2013

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References

1.Butler, A, Olsen, M, Merz, L, Guth, R, Woeltje, K, Camins, B, Fraser, V. Attributable costs of enterococcal bloodstream infections in a nonsurgical hospital cohort. Infect Control Hosp Epidemiol 2010;31(1):28–35.Google Scholar
2.Garbutt, J, Littenberg, B, Evanoff, B, Sahm, D, Mundy, L. Enteric carriage of vancomycin-resistant Enterococcusfaecium in patients tested for Clostridium difficile. Infect Control Hosp Epidemiol 1999;20(10):664–670.Google Scholar
3.Ray, A, Hoyen, C, Das, S, Eckstein, E, Donskey, C. Undetected vancomycin-resistant enterococcus stool colonization in a Veterans Affairs hospital using a Clostridium difficile-focused surveillance strategy. Infect Control Hosp Epidemiol 2002;23(8):474–477.Google Scholar
4.Burger, T, Fry, D, Fusco, R, et al.Multihospitals surveillance of nosocomial methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus, and Clostridium difficile, analysis of a 4-year data sharing project, 1999-2002. Am J Infect Control 2006;34(7):458–454.Google Scholar
5.Sheetz, M, Knechtel, SA, Malczynski, M, Postelnick, MJ, Qi, C. Increasing incidence of linezolid-intermediate or -resistant, vancomycin-resistant Enterococcus faecium strains parallels increasing linezolid consumption. Antimicrob Agents Chemother 2008; 52(6):2256–2259.Google Scholar
6.Ajao, A, Harris, A, Roghman, M, et al.Systematic review of measurement and adjustment for colonization pressure in studies of methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococci, and Clostridium difficile acquisition. Infect Control Hosp Epidemiol 2011;32(5):481–489.Google Scholar
7.Wagner, A, Soumerai, S, Zhang, F, Ross-Dengan, D. Segmented regression analysis of interrupted time series studies in medication use research. J Clin Pharm Ther 2002:27(4):299–309.Google Scholar
8.Muto, C, Jernigan, J, Ostrowsky, B, et al.SHEA guideline for preventing nosocomial transmission of multi-drug resistant strains of Staphylococcus aureus and Enterococcus. Infect Control Hosp Epidemiol 2003;24(5):362–386.Google Scholar
9.Siegel, JD, Rhinehart, E, Jackson, M, Chiarello, L. Management of multi drug-resistant organisms in healthcare settings, 2006. Am J Infect Control 2007;35(10)(suppl):S65–S194.Google Scholar
10.Calfee, D, Gianetta, E, Durbin, L, Germanson, T, Farr, B. Control of endemic vancomycin-resistant Enterococcus among inpatients at a university hospital. Clin Infect Dis 2003:37(3):326–332.Google Scholar
11.Lucet, JC, Armand-Lefevre, L, Laurichesse, JJ, et al.Rapid control of an outbreak of vancomycin-resistance Enterococci in a French university hospital. J Hosp Infect 2007;67(1):42–48.Google Scholar