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Diagnostic Characteristics of Routine Surveillance Cultures of Endotracheal Aspirate Samples in Cases of Late-Onset Ventilator-Associated Pneumonia Due to Acinetobacter baumannii

Published online by Cambridge University Press:  02 January 2015

Paolo Malacarne*
Affiliation:
Unitá Operativa Anestesia e Rianimazione Azienda Ospedaliera—Universitaria Pisana, Pisa, Italy
Marzia Corini
Affiliation:
Unitá Operativa Anestesia e Rianimazione Azienda Ospedaliera—Universitaria Pisana, Pisa, Italy
Paolo Maremmani
Affiliation:
Unitá Operativa Anestesia e Rianimazione Azienda Ospedaliera—Universitaria Pisana, Pisa, Italy
Bruno Viaggi
Affiliation:
Unitá Operativa Anestesia e Rianimazione Azienda Ospedaliera—Universitaria Pisana, Pisa, Italy
Simone Verdigi
Affiliation:
Unitá Operativa Anestesia e Rianimazione Azienda Ospedaliera—Universitaria Pisana, Pisa, Italy
*
Unitá Operativa Anestesia e Rianimazione Azienda Ospedaliera Universitaria Pisana, Pisa, Italy ([email protected])

Abstract

Of 20 consecutive episodes of ventilator-associated pneumonia due to Acinetobacter baumannii, 18 were preceded by tracheobronchial colonization with strains ofA. baumannii that had the same antibiotic susceptibility pattern. When the results of routine surveillance cultures of endotracheal aspirate samples were compared with the results of bronchoalveolar lavage fluid cultures performed for patients who developed late-onset ventilator-associated pneumonia, the sensitivity of the surveillance cultures was 90%, and the negative predictive value was 96%. The positive predictive value of surveillance cultures for identifying causative pathogens in cases of pneumonia due to A. baumannii was good.

Type
Concise Communications
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2007

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References

1.Wilks, M, Wilson, A, Warwick, S, et al.Control of an outbreak of multidrug-resistant Acinetobacter baumannii-calcoaceticus colonization and infection in an intensive care unit (ICU) without closing the ICU or placing patients in isolation. Infect Control Hosp Epidemiol 2006;27:654658.Google Scholar
2.Michel, F, Franceschini, B, Berger, P, et al.Early antibiotic treatment for BAL-confirmed ventilator-associated pneumonia. Chest 2005;127:589597.Google Scholar
3.Dupuydt, PO, Stijin, I, Blot, P, et al.Antimicrobial resistance in nosocomial bloodstream infection associated with pneumonia and the value of systematic surveillance cultures in an adult intensive care unit. Crit Care Med 2006;34:653659.CrossRefGoogle Scholar
4.Delcloux, C, Roupie, E, Blot, F, Brochard, L, Lemaire, F, Brun-Buisson, C. Lower respiratory tract colonization and infection during severe acute respiratory distress syndrome: incidence and diagnosis. Am J Respir Crit Care Med 1997;156:10921098.Google Scholar
5.Bouza, E, Perez, A, Munoz, P, et al.Ventilator-associated pneumonia after heart surgery: a prospective analysis and the value of surveillance. Crit Care Med 2003;31:19641970.CrossRefGoogle ScholarPubMed
6.Kollef, MH, Sherman, G, Ward, S, Fraser, VJ. Inadequate antimicrobial treatment of infections: a risk factor for hospital mortality among critically ill Patients. Chest 1999;115:462474.Google Scholar
7.Dannesen, PJ, van der Ven, AJ, Kessel, AG, Ramsay, G, Bonten, M. Resolution of infectious parameters after antimicrobial therapy in patients with ventilator-associated pneumonia. Am J Respir Crit Care Med 2001;163:13711375.CrossRefGoogle Scholar
8.Hayon, I, Figliolini, C, Combes, A, et al.Role of serial routine microbiologic culture results in the initial management of management of ventilator-associated pneumonia. Am J Respir Crit Care Med 2002;165:4146.Google Scholar
9.Crnich, C, Proctor, R. Ventilator-associated pneumonia: does surveillance have a role in its management? Crit Care Med 2003;31:24112412.Google Scholar
10.Relio, J. Acinetobacter baumannii infections in the ICU. Chest 1999;115:12261229.Google Scholar