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Antimicrobial resistance patterns in urinary E. coli isolates after a change in a single center’s guidelines for uncomplicated cystitis in ambulatory settings

Published online by Cambridge University Press:  21 March 2019

Patrick P. Ryan Open the ORCID record for Patrick P. Ryan [Opens in a new window] ,
Bryan C. Knepper ,
Rachel M. Everhart  and
Connie S. Price
Patrick P. Ryan*
Affiliation:
Department of General Internal Medicine, Denver Health and Hospital Authority, Denver, Colorado Ambulatory Care Services, Community Health Services, Denver Health and Hospital Authority, Denver, Colorado University of Colorado School of Medicine, Aurora, Colorado
Bryan C. Knepper
Affiliation:
Department of Patient Safety and Quality, Denver Health and Hospital Authority, Denver, Colorado
Rachel M. Everhart
Affiliation:
Ambulatory Care Services, Community Health Services, Denver Health and Hospital Authority, Denver, Colorado
Connie S. Price
Affiliation:
University of Colorado School of Medicine, Aurora, Colorado Division of Infectious Diseases, Department of Medicine, Denver Health and Hospital Authority, Denver, Colorado
*
Author for correspondence: Patrick Ryan, Email: [email protected]
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Abstract

Recommending nitrofurantoin to treat uncomplicated cystitis was associated with increased nitrofurantoin use from 3.53 to 4.01 prescriptions per 1,000 outpatient visits, but nitrofurantoin resistance in E. coli isolates remained stable at 2%. Concomitant levofloxacin resistance was a significant risk for nitrofurantoin resistance in E. coli isolates (odds ratio [OR], 2.72; 95% confidence interval [CI], 1.04–7.17).

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 40 , Issue 5 , May 2019 , pp. 600 - 602
Copyright
© 2019 by The Society for Healthcare Epidemiology of America. All rights reserved. 

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Footnotes

Previous Presentation: This work was previously presented in a poster at IDWeek 2016 on October 28, 2016, in New Orleans, Louisiana.

References

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