When Alexander VI promulgated the bull Inter caetera on May 4, 1493 granting Spain a large part of the new world, there seems to have been no doubt that the natives who dwelt in the ‘very remote islands and mainlands’ would be willing and able to accept the teachings of the Catholic church. For Alexander had been informed that in those far off lands were
very many peoples living in peace and, as reported, going unclothed, and not eating flesh. Moreover, … these very peoples … believe in one God the Creator in heaven, and seem sufficiently disposed to embrace the Catholic faith and be trained in good morals. And it is hoped that, were they instructed, the name of the Savior, our Lord Jesus Christ, would easily be introduced into the said countries and islands.
These optimistic predictions were not fulfilled and, as the Spanish conquest of the Americas proceeded to reveal the existence of millions of natives, the action of the papacy in the conversion and protection of these masses of Indians became an important matter, for as that studious seventeenth century jurist, Antonio de Leon Pinelo, declared:
Inasmuch as the Indies were conceded to the kings of Castile principally in order to favor and convert the Indians, no harm must come of this concession.