Research Protocols or Methods Papers are detailed descriptions of research methods with a focus on helping other researchers to use and reproduce methodology, rather than presenting results, testing hypotheses or providing new interpretations. 

Methods Papers should include a detailed description of protocols, incorporating specific technical details necessary to ensure reproducibility, and the results of a validation study. In order to demonstrate a practical relevance, Methods Papers must show an application of the method to an important biological question and demonstrate its advantage or equivalence compared to existing approaches. Validation of the method and demonstration of comparable or superior results over existing techniques most often involve novel biologically relevant data. However, since the focus is on the technology, providing significant new insights into a biological problem is not a requirement.

Articles should follow the format below:

• Abstract
• Background/Relevance
• Protocol
• Validation
• Usage Notes (optional)
• Code Availability
• References

To submit your paper, please visit the GMB ScholarOne site here.