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Utilization and interconversions of purine derivatives in the fission yeast Schizosaccharomyces pombe

Published online by Cambridge University Press:  14 April 2009

J. Pourquié  and
H. Heslot
J. Pourquié
Affiliation:
Laboratoire de Génétique, Institut National Agronomique, 16 Rue Claude Bernard, Paris 5°, France
H. Heslot
Affiliation:
Laboratoire de Génétique, Institut National Agronomique, 16 Rue Claude Bernard, Paris 5°, France
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Summary

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In the fission yeast Schizosaccharomyces pombe, growth responses of mutants strains in the de novo purine synthesis pathway, in the purine interconversion system, and of various double mutants, have been studied upon different purine-supplemented media. The results show that exogenous purine utilization as nucleotide source is based exclusively upon pyrophosphorylation of purine bases, and they make it possible to identify most of the enzymic steps acting, in this organism, upon a purine ring to give another purine ring.

A scheme of the interconversion system in Schizosaccharomyces pombe is given.

Type
Research Article
Information
Genetics Research , Volume 18 , Issue 1 , August 1971 , pp. 33 - 44
Copyright
Copyright © Cambridge University Press 1971

References

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