Hostname: page-component-586b7cd67f-dlnhk Total loading time: 0 Render date: 2024-11-28T00:43:59.480Z Has data issue: false hasContentIssue false

Transduction analysis using leucine requiring mutants of Salmonella typhimurium

Published online by Cambridge University Press:  14 April 2009

P. F. Smith-Keary
Affiliation:
Department of Genetics, Trinity College, Dublin
G. W. P. Dawson
Affiliation:
Department of Genetics, Trinity College, Dublin
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

1. Data is presented in support of the hypothesis that in Salmonella typhimurium the fragments participating in the transduction of a particular linkage group arise by breakages at constant positions in the genome of the donor bacteria.

2. Data from three factor transduction experiments are used to construct a linkage map of the leu-araB region which defines not only the relative order of the markers but also the relative distances between them.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1963

References

REFERENCES

Dawson, G. W. P. (1963). The interpretation of data from transduction experiments. Genet. Res. 4, 416426.CrossRefGoogle Scholar
Dawson, G. W. P. & Smith-Keary, P. F. (1960). Analysis of the su-leuA locus in Salmonella typhimurium. Heredity, 15, 339350.Google Scholar
Demerec, M. (1960). Frequency of deletions among spontaneous and induced mutation in Salmonella. Proc. not. Acad. Sci., Wash., 48, 10751079.CrossRefGoogle Scholar
Freundlich, M., Brausrs, R. O. & Umbarger, H. E. (1962). Control of isoleucine, valine, and leucine biosynthesis, I. Multi-valent repression. Proc. nat. Acad. Sci., Wash., 48, 18041808.CrossRefGoogle Scholar
Gross, S. R., Jungwirth, C. & Umbarger, E. (1962). Another intermediate in leucine biosynthesis. Biochem. Biophys. Res. Comm. 7, 59.CrossRefGoogle ScholarPubMed
Margolin, P., Vandermeulen-Cocito, J. & Simrell, E. J. (1960). The leucine locus of Salmonella typhimurium. Ann. Rept. Biol. Lab. (Cold Spring Harbor), 1958–1959, 4143.Google Scholar
Ozeki, H. (1959). Chromosome fragments participating in transduction in Salmonella typhimurium. Genetics, 44, 458470.CrossRefGoogle ScholarPubMed
Pritchard, R. H. (1959). Localized negative interference and its bearing on models of gene recombination. Genet. Res. 1, 124.CrossRefGoogle Scholar
Pritchard, R. H. (1960). The bearing of recombination analysis at high resolution on genetic fine structure in Aspergillus nidulans and the mechanism of recombination in higher organisms. In Microbial Genetics, Symp. Soc. gen. Microbiol., 10, 155180.Google Scholar
Smith-Keary, P. F. (1960). A suppressor of leucineless in Salmonella typhimurium. Heredity, 14, 6171.Google Scholar
Witkin, E. M. (1956). Time, temperature, and protein synthesis: a study of ultraviolet-induced mutation in bacteria. Cold Spr. Harb. Symp. quant. Biol. 21, 123138.CrossRefGoogle ScholarPubMed