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Tipsy, a new mutant in linkage group VII of the mouse

Published online by Cambridge University Press:  14 April 2009

A. G. Searle
A. G. Searle
Affiliation:
Medical Research Council Radiobiological Research Unit, Harwell, Berkshire, England
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Tipsy (symbol ti) is a fully penetrant recessive mutant in linkage group VII of the mouse. Homozygotes have a peculiar rabbit-like gait from the age of a week, followed soon after by a tendency for the fore-part of the body to sway from side to side, leading to a reeling locomotion with falling over in severely affected mice. There is marked variation in manifestation and some amelioration in older animals; both sexes are fertile.

Linkage relationships in group VII are discussed and tipsy is compared with other mutants showing locomotor instability.

Type
Research Article
Information
Genetics Research , Volume 2 , Issue 1 , February 1961 , pp. 122 - 126
Copyright
Copyright © Cambridge University Press 1961

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