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Tandem duplications in Drosophila melanogaster: III. Intrachromosomal exchange of a heterozygous tandem duplication

Published online by Cambridge University Press:  14 April 2009

Wolf-Ekkehard Kalisch
Wolf-Ekkehard Kalisch
Affiliation:
Lehrstuhl für Genetik der Ruhr-Universität Bochum, D-463 Bochum, Federal Republic of Germany
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Summary

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During meiosis the two parts of a tandem duplication are able to pair in a double loop instead of pairing with the corresponding region of the homologous chromosome. The frequency of intrachromosomal exchange within this double loop was measured in heterozygous females of tandem duplication Dp(1; 1)Gr by the phenotypes of the exceptional F1 males. The intrachromosomal exchange frequency is increased significantly by both the ‘interchromosomal effect’ of heterozygous inversions in the autosomes and by a double inversion in the homologous X chromosome. Distribution of the exchange events depends on the pairing situation and its frequency within the double loop. The analysis of clusters of intrachromosomal recombinants observed favours the assumption that this exchange type is exclusively a meiotic event.

Type
Research Article
Information
Genetics Research , Volume 26 , Issue 3 , December 1975 , pp. 275 - 282
Copyright
Copyright © Cambridge University Press 1975

References

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