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Suppressor-specificity of antisuppressors in yeast

Published online by Cambridge University Press:  14 April 2009

Shirley J. McCready  and
Brian Cox
Shirley J. McCready
Affiliation:
Botany School, Oxford
Brian Cox
Affiliation:
Botany School, Oxford
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Summary

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Eighteen mutations of Saccharomyces cerevisiae, at eight loci, isolated as antisuppressors of SUPQ2, an ochre-suppressing allele of SUP11, were crossed with three other suppressors.

They were found to abolish the ability of SUP2 (inserting tyrosine), to suppress the ochre mutations ade2.1 and can1.100, but not its ability, to suppress his5.2 or lys1.1. When coupled with any antisuppressor, SUPQ5, inserting serine, was also unable to suppress ade2.1, but the suppression of other ochre mutations varied from one asu-SUPQ5 strain to another. No antisuppressor affected the ability of SUP11-am, an amber-suppressing allele of SUP11, to suppress trp1.1, an amber mutation.

Type
Research Article
Information
Genetics Research , Volume 28 , Issue 2 , October 1976 , pp. 129 - 138
Copyright
Copyright © Cambridge University Press 1976

References

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