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Studies on male recombination in a Southern Greek Drosophila melanogaster population

(c) Chromosomal abnormalities at male meiosis (d) Cytoplasmic factor responsible for the reciprocal cross effect

Published online by Cambridge University Press:  14 April 2009

George Yannopoulos
George Yannopoulos
Affiliation:
Department of Genetics, University of Cambridge, England
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A combined cytological and genetic analysis has been carried out to determine whether the spontaneous male recombination associated with a line of Drosophila melanogaster derived from Southern Greece (31.1 MRF) involves chromosome breakage and random reunion. In all crosses showing male recombination, extensive abnormalities involving anaphase bridges and fragments were found at first and second meiotic divisions. This confirms that the low level of recombination associated with male recombination lines is not produced by normal, controlled crossing-over of the type found in females, but by chance reunions, following more erratic breakage events at first and second anaphase. In addition the occurrence of some limited premeiotic recombination cannot be excluded. The 31.1 MRF system shows higher recombination levels at elevated temperatures (29 °C) and chromosome abnormality frequency is also greatly increased. The 31.1 MRF induces both male recombination and chromosomal abnormalities at meiosis when it is inherited from females deriving their cytoplasm from stock other than CyL4/Pm. It is concluded that this factor acts independently of sex and that the reciprocal cross effect is caused by a cytoplasmic factor which the 31.1/CyL4 strain inherited from the CyL4/Pm stock.

Type
Research Article
Information
Genetics Research , Volume 31 , Issue 2 , April 1978 , pp. 187 - 196
Copyright
Copyright © Cambridge University Press 1978

References

REFERENCES

Broadwater, G., Owens, L. V., Parks, R., Winfrey, E. & Waddle, F. R. (1973). Male recombination from natural populations of Drosophila melanogaster from North Carolina. Drosophila Information Service 50, 99.Google Scholar
Cardellino, R. A. & Mukai, T. T. (1975). Mutator factors and genetic variance components of viability in Drosophila melanogaster. Genetics 80, 567–583.CrossRefGoogle ScholarPubMed
Cooper, K. W. (1965). ‘Normal spermatogenesis in Drosophila.’ In Biology of Drosophila. New York, London: Hafner.Google Scholar
Franca, Z. M., Dacunha, A. B. & Garrido, M. C. (1968). Recombinations in Drosophila willistoni. Journal of Heredity 23, 199–204.CrossRefGoogle ScholarPubMed
Green, M. M. (1977). Genetic instability in Drosophila melanogaster: De novo induction of putative insertion mutations. Proceedings of the National Academy of Sciences, U.S.A. 74, 3490–3493.CrossRefGoogle ScholarPubMed
Henderson, A. S., Woodruf, R. C. & Thompson, J. N. Jr (1977). Spontaneous chromosome breakage at male meiosis associated with male recombination in Drosophila melanogaster. Genetics (In the press.)Google Scholar
Hinton, C. W. & Downs, J. E. (1975). The mitotic, polytene, and meiotic chromosomes of Drosophila ananassae. Journal of Heredity 66, 353–361.CrossRefGoogle ScholarPubMed
Hiraizumi, Y. (1971). Spontaneous recombination in Drosophila melanogaster males. Proceedings of the National Academy of Sciences, U.S.A. 68, 268–270.CrossRefGoogle ScholarPubMed
Kidwell, M. G. & Kidwell, J. F. (1975 a). Cytoplasmic–chromosome interactions in Drosophila melanogaster. Nature 253, 755–756.CrossRefGoogle Scholar
Kidwell, M. G. & Kidwell, J. F. (1975 b). Spontaneous male recombination and mutation in isogenic-derived chromosomes of Droaophila melanogaster. Journal of Heredity 66, 367–375.CrossRefGoogle ScholarPubMed
Kidwell, M. G., Kidwell, J. F. & Ives, T. P. (1977). Spontaneous non-reciprocal mutations and sterility in strains crosses of Drosophila melanogaster. Mutation Research 42, 89–98.CrossRefGoogle Scholar
Kidwell, M. G., Kidwell, J. F. & Sved, J. A. (1977). Hybrid dysgenesis in Drosophila melanogaster: A syndrome of aberrant traits including mutation, sterility and male recombination. Genetics 86, 813–833.CrossRefGoogle ScholarPubMed
Kikkawa, H. (1935). Crossing-over in the male of Drosophila virilis. Cytologia 6, 190–194.CrossRefGoogle Scholar
Lindsley, D. L. & Grell, E. H. (1968). Genetic variation of Drosophila melanogaster. Carnegie Institute of Washington Publication, p. 627.Google Scholar
Matthews, J. A. & Hiraizumi, Y. (1976). Frequency of male recombination element (Mr) in a South Texas population of Drosophila melanogaster. Genetics 83, s48.Google Scholar
Moriwaki, D. & Tobari, Y. N. (1975). Drosophila ananassae. In Handbook of Genetics, vol. III (ed. King, R. C.). New York: Plenum Press.Google Scholar
Nichols, W. W. (1974). Viruses and chromosomes. In The Cell Nucleus, vol. II (ed. Harris, Busch). Academic Press.Google Scholar
Philip, U. (1944). Crossing over in the males of Drosophila subobscura. Nature 153, 223.CrossRefGoogle Scholar
Roberts, P. A. (1976). The genetics of chromosomal aberration. In The Genetics and Biology of Drosophila, vol. Ia (ed. Ashburner, M. and Novitski, E.), pp. 67–184.Google Scholar
Slatko, B. E. & Hiraizumi, Y. (1973). Mutation induction in the male recombination strains of Drosophila melanogaster. Genetics 75, 643–649.CrossRefGoogle ScholarPubMed
Sochacka, J. H. N. & Woodruff, R. C. (1976). Induction of male recombination in Drosophila melanogaster by injection of extracts of flies showing male recombination. Nature 262, 287–289.CrossRefGoogle ScholarPubMed
Sved, J. A. (1974). Association between male recombination and rabid mutational changes in Drosophila melanogaster. Genetics 77, s64.Google Scholar
Sved, J. A. (1976). Hybrid dysgenesis in Drosophila melanogaster: a possible explanation in terms of spatial organisation of chromosomes. Australian Journal of Biological Science 29, 375–386.CrossRefGoogle ScholarPubMed
Voelker, R. A. (1974). The Genetics and Cytology of amutator factor in Drosophila melanogaster. Mutation Research 22, 265–276.CrossRefGoogle ScholarPubMed
Waddle, F. R. & Oster, I. I. (1974). Autosomal recombination in males of Drosophila melanogaster caused by a transmissible factor. Journal of Genetics, 61, 177–183.CrossRefGoogle Scholar
Woodruff, R. C. & Bortolozi, J. (1976). Spontaneous recombination in males of Drosophila simulans. Heredity 37, 295–298.CrossRefGoogle ScholarPubMed
Woodruff, R. C. & Thompson, J. N. Jr (1977). An analysis of spontaneous recombination in Drosophila melanogaster males. Isolation and characterization of male recombination lines. Heredity 38, 291–307.CrossRefGoogle Scholar
Yamaguchi, O. (1976). Spontaneous chromosome mutations and screening of mutator factors in Drosophila melanogaster. Mutation Research 34, 389–406.CrossRefGoogle ScholarPubMed
Yamaguchi, O. & Mukai, T. (1974). Variation of spontaneous occurrence rates of chromosomal aberrations in the second chromosomes of Drosophila melanogaster. Genetics 78, 1209–1221.CrossRefGoogle ScholarPubMed
Yannopoulos, G. & Pelecanos, M. (1977). Studies on male recombination in a Southern Greek Drosophila melanogaster population, (a) Effect of temperature, (b) Suppression of male recombination in reciprocal crosses. Genetical Research 29, 231–238.CrossRefGoogle Scholar