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Studies on genetic organization in higher organisms: III. Confirmation of the single cistron-allele complementation model of organization of the maroon-like region of Drosophila melanogaster*

Published online by Cambridge University Press:  14 April 2009

Victoria Finnerty
Affiliation:
Genetics and Cell Biology, University of Connecticut, Storrs, Connecticut 06268
Arthur Chovnick
Affiliation:
Genetics and Cell Biology, University of Connecticut, Storrs, Connecticut 06268
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Summary

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A genetic fine-structure experiment on Drosophila melanogaster is described, which makes use of a lethal selective system which permits survival only of recombinants in the ma-l region, including exchanges between site mutants of ma-l. On the basis of prior mapping information, the experiment was designed to select for ma-l double mutant recombinants. Utilizing a pair of complementing ma-l mutants, double mutant meiotic products were recovered whose complementation properties provide independent support for the single-cistron, allele complementation model of organization of the maroon-like region inferred from other experiments described earlier.

Type
Short Papers
Copyright
Copyright © Cambridge University Press 1970

References

REFERENCES

Brosseau, G. E., Nicoletti, B., Grell, E. H. & Lindsley, D. L. (1961). Production of altered Y chromosomes bearing specific sections of the X chromosome in Drosophila. Genetics, Princeton 46, 339–46.Google Scholar
Chovnick, A., Finnerty, V., Schalet, A. & Duck, P. (1969). Studies on genetic organization in higher organisms. I. Analysis of a complex gene in Drosophila melanogaster. Genetics, Princeton 62, 145–60.Google Scholar
Chovnick, A. & Sang, J. H. (1968). The effects of nutritional deficiencies on the maroon-like maternal effect in Drosophila. Genet. Res. 11, 5161.Google Scholar
Courtright, James B. (1967). Polygenic control of aldehyde oxidase in Drosophila. Genetics, Princeton 57, 2539.Google Scholar
Finnerty, V., Duck, P. & Chovnick, A. (1970). Studies on genetic organization in higher organisms. II. Complementation and fine structure of the maroon-like locus of Drosophila melanogaster. Proc. Natn. Acad. Sci. U.S.A. (in the Press).Google Scholar
Forrest, H. S., Hanly, E. W. & Lagowski, J. M. (1961). Biochemical differences between mutants rosy-2 and maroon-like of Drosophila melanogaster. Genetics, Princeton 46, 1455–63.Google Scholar
Glassman, E. (1965). Genetic regulation of xanthine dehydrogenase in Drosophoila melanogaeter. Fed Proc. Fedn Am. Socs. exp. Biol. 24, 1243–51.Google Scholar
Glassman, E. & Mitchell, H. K. (1959). Mutants in Drosophila melanogaster deficient in xanthine dehydrogenase. Genetics, Princeton 44, 153–62.Google Scholar
Lindsley, D. L. & Grell, E. H. (1967). Genetic variations of Drosophila melanogaster. Publs. Carnegie Inst. no. 627.Google Scholar
Schalet, A. & Finnerty, V. (1968). The arrangement of genes in the proximal region of the X chromosome of Drosophila melanogaster. Drosop. Inf. Serv. 43, 128–9.Google Scholar