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The structure of hair and follicles of mice carrying the naked (N) gene

Published online by Cambridge University Press:  14 April 2009

Kathryn A. Raphael ,
R. E. Chapman ,
Penelope A. Frith  and
Pamela R. Pennycuik
Kathryn A. Raphael
Affiliation:
CSIRO, Genetics Research Laboratories, P.O. Box 184, North Ryde, N.S.W., 2113, Australia.
R. E. Chapman
Affiliation:
CSIRO, Division of Animal Production, P.O. Box 239, Blacktown, N.S.W., 2148, Australia
Penelope A. Frith
Affiliation:
CSIRO, Division of Animal Production, P.O. Box 239, Blacktown, N.S.W., 2148, Australia
Pamela R. Pennycuik
Affiliation:
CSIRO, Genetics Research Laboratories, P.O. Box 184, North Ryde, N.S.W., 2113, Australia.
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Summary

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The hairs and follicles from mice carrying the naked (N) gene have been examined using both scanning and transmission electron microscopy in addition to light microscopy. Fibre cuticle cells and occasionally cortical cells were absent from the follicles of N / + mice when the base of the hair was growing. In N / N follicles there was a frequent lack of both cuticle and cortical cells throughout the growth phase of the follicles. Abnormalities were also observed in the manner in which the synthesized keratin was deposited in the fibres. The possible mode of action of the N gene is discussed in the light of these results.

Type
Research Article
Information
Genetics Research , Volume 39 , Issue 2 , April 1982 , pp. 139 - 148
Copyright
Copyright © Cambridge University Press 1982

References

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