Hostname: page-component-586b7cd67f-r5fsc Total loading time: 0 Render date: 2024-11-24T06:40:48.402Z Has data issue: false hasContentIssue false
  • English
  • Français

Sterility-mutability correlation: On the correlation between sterility and mutability during P-M hybrid dysgenesis in Drosophila melanogaster

Published online by Cambridge University Press:  14 April 2009

Gail M. Simmons
Gail M. Simmons
Affiliation:
Department of Genetics, University of California, Davis, California 95616, U.S.A.
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Twelve isogenic X chromosome lines from a single natural population of Drosophila melanogaster were tested for their potential to induce gonadal dysgenesis and singed-weak mutability in P-M hybrid dysgenesis. The correlation between sterility and mutability was significantly positive for Cross A, confirming the results reported by Engels (1984) and Kocur, Drier & Simmons (1986). In Cross A* cytotype tests, however, two of the lines gave strikingly different results when measured by the gonadal dysgenesis test as compared to the singed-weak test. Positive correlations between traits within a given line were generally not observed. The results suggest that the relationship between gonadal dysgenesis production and the mobilization of P elements in singed-weak mutability is more complicated than that proposed by Engels (1984). The two phenomena may be separable under certain conditions. Neither test can be taken as an adequate characterization of the hybrid dysgenesis ‘profile’ of a line of flies.

Type
Short Paper
Information
Genetics Research , Volume 50 , Issue 1 , August 1987 , pp. 73 - 76
Copyright
Copyright © Cambridge University Press 1987

References

Bingham, P. M., Kidwell, M. G. & Rubin, G. M. (1982). The molecular basis of P-M hybrid dysgenesis: the role of the P element, a P strain-specific transposable element family. Cell 29, 995–1004.CrossRefGoogle Scholar
Bregliano, J. C. & Kidwell, M. G. (1983). Hybrid dysgenesis determinants. In Mobil Genetic Elements (ed. Shapiro, J. A.), pp. 363–410. New York: Academic Press.Google Scholar
Engels, W. R. (1979 a). Hybrid dysgenesis in Drosophila melanogaster: rules of inheritance of female sterility. Genetical Research 33, 219–236.CrossRefGoogle Scholar
Engels, W. R. (1979 b). The estimation of mutation rates when premeiotic events are involved. Environmental Mutagenesis 1, 37–43.CrossRefGoogle ScholarPubMed
Engels, W. R. (1981). Germline hypermutability in Drosophila and its relation to hybrid dysgenesis and cytotype. Genetics 98, 565–587.CrossRefGoogle ScholarPubMed
Engels, W. R. (1983). The P family of transposable elements in Drosophila. Annual Review of Genetics 17, 315–344.CrossRefGoogle Scholar
Engels, W. R. (1984). A trans-acting product needed for P factor transposition in Drosophila. Science 226, 1194–1196.CrossRefGoogle ScholarPubMed
Green, M. M. (1977). Genetic instability in Drosophila melanogaster: de novo induction of putative insertion mutants. Proceedings of the National Academy of Sciences, USA 74, 3490–3493.CrossRefGoogle Scholar
Green, M. M. (1984). Genetic instability in Drosophila melanogaster: on the identity of the MR and P-M mutator systems. Biologisches Zentrallblatt 103, 1–8.Google Scholar
Kidwell, M. G. (1983). Hybrid dysgenesis in Drosophila melanogaster: factors affecting chromosomal contamination in the P-M system. Genetics 104, 317–341.CrossRefGoogle ScholarPubMed
Kidwell, M. G. (1985). Hybrid dysgenesis in Drosophila melanogaster: nature and inheritance of P element regulation. Genetics 111, 337–350.CrossRefGoogle ScholarPubMed
Kidwell, M. G., Kidwell, J. F. & Sved, J. A. (1977). Hybrid dysgenesis in Drosophila melanogaster: a syndrome of aberrant traits including mutation, sterility, and male recombination. Genetics 86, 813–833.CrossRefGoogle ScholarPubMed
Kocur, G. J., Drier, E. A. & Simmons, M. J. (1986). Sterility and hypermutability in the P-M system of hybrid dysgenesis in Drosophila melanogaster. Genetics 114, 1147–1163.CrossRefGoogle Scholar
Lindsley, D. H. & Grell, E. H. (1968). Genetic variations of Drosophila melanogaster. Carnegie Institution of Washington Publication No. 627.Google Scholar
Rio, D. C., Laski, F. A. & Rubin, G. M. (1986). Identification and immunochemical analysis of biologically active Drosophila P element transposase. Cell 44, 21–32.CrossRefGoogle ScholarPubMed
Siegel, S. (1956). Nonparametric Statistics for the Behavioral Sciences. New York: McGraw-Hill.Google Scholar
Simmons, G. M. (1985). The genetics of P-M hybrid dysgenesis in a natural population of Drosophila melanogaster. Ph.D. dissertation, University of California, Davis, California.Google Scholar
Simmons, G. M. (1986). Gonadal dysgenesis determinants in a natural population of Drosophila melanogaster. Genetics 114, 897–918.CrossRefGoogle Scholar
Slatko, B. & Hiraizumi, Y. (1973). Mutation induction in male recombination strains of Drosophila melanogaster. Genetics 75, 643–649.CrossRefGoogle ScholarPubMed