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A stable duplication of the rII region of bacteriophage T4

Published online by Cambridge University Press:  14 April 2009

C. van de Vate
Affiliation:
School of Biological Sciences, University of Sussex, Brighton, Sussex
P. van den Ende
Affiliation:
School of Biological Sciences, University of Sussex, Brighton, Sussex
N. Symonds
Affiliation:
School of Biological Sciences, University of Sussex, Brighton, Sussex
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Summary

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In the preceding paper (Van de Vate & Symonds, 1974) a deletion, sdl, has been reported that stabilizes an rII diploid by penetrating into the region of the duplication from the right-hand side (if we take the rIIB gene located to the right of rIIA). Here we wish to report on a different stabilizing deletion, sd2. Evidence will be presented in favour of penetration of the duplication from the left-hand side. The right-hand terminus of the deletion is located within the rIIA gene.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1974

References

REFERENCES

Brody, E., Sederoff, R., Bolle, A. & Epstein, R. H. (1970). Early transcription in T4-infected cells. Cold Spring Harbor Symposium on Quantitative Biology 35, 203211.CrossRefGoogle Scholar
Champe, S. P. & Benzer, S. (1962). An active cistron fragment. Journal of Molecular Biology 4, 288292.CrossRefGoogle ScholarPubMed
Edgar, R. S. & Wood, W. B. (1966). Morphogenesis of bacteriophage T4 in extracts of mutant-infected cells. Proceedings of the National Academy of Sciences, U.S.A. 55, 498505.CrossRefGoogle ScholarPubMed
Schmidt, D. A., Mazaitis, A. J., Kasai, T. & Bautz, E. K. F. (1970). Involvement of a phage T4 factor and an anti-terminator protein in the transcription of early T4 genes in vivo. Nature 225, 10121016.Google Scholar
Sederoff, R., Bolle, A. & Epstein, R. H. (1971 a). A method for the detection of specific T4 messenger RNAs by hybridization competition. Virology 45, 440455.CrossRefGoogle ScholarPubMed
Sederoff, R., Bolle, A., Goodman, H. M. & Epstein, R. H. (1971 b). Regulation of rII and region D transcription in T4 bacteriophage: A sucrose gradient analysis. Virology 46, 817829.Google Scholar
Symonds, N., Van den Ende, P., Durston, A. & White, P. (1972). The structure of rII diploids of phage T4. Molecular and General Genetics 116, 223238.CrossRefGoogle ScholarPubMed
Van de Vate, C. & Symonds, N. (1974). A stable duplication as an intermediate in the selection of deletion mutants of phage T4. Genetical Research 23, 87105.CrossRefGoogle Scholar
Weil, J. & Terzaghi, B. (1970). The correlated occurrence of duplications and deletions in phage T4. Virology 42, 234237.CrossRefGoogle ScholarPubMed