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Somatic reversion of P transposable element insertion mutations in the singed locus of Drosophila melanogaster requiring specific P insertions and a trans- acting factor

Published online by Cambridge University Press:  14 April 2009

John F. Y. Brookfield  and
Alan P. Lewis
John F. Y. Brookfield*
Affiliation:
Department of Genetics, University of Nottingham, Queens Medical Centre, Nottingham NG7 2UH, UK
Alan P. Lewis
Affiliation:
Department of Genetics, University of Nottingham, Queens Medical Centre, Nottingham NG7 2UH, UK
*
† Corresponding author.
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Destabilization in somatic cells of P-element insertions in the X-linked singed gene of Drosophila melanogaster has been studied. We have shown that some but not all unstable P-element insertions in singed can form mosaics. The cause of this variation is not clear from studies of the restriction maps of the mutations tested. The transposable element movements occur early in development and require, in addition to an appropriate P-element insertion in singed, a trans-acting maternal effect component. Movements appear to occur preferentially in attached-X stocks. However, the maternal effect component maps to the central region of chromosome 2.

Type
Research Article
Information
Genetics Research , Volume 54 , Issue 2 , October 1989 , pp. 101 - 112
Copyright
Copyright © Cambridge University Press 1989

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