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Simulation of marker assisted selection for non-additive traits

Published online by Cambridge University Press:  14 April 2009

A. Gimelfarb  and
R. Lande
A. Gimelfarb
Affiliation:
Department of Biology, University of Oregon, Eugene, Oregon 97403, U.S.A.
R. Lande*
Affiliation:
Department of Biology, University of Oregon, Eugene, Oregon 97403, U.S.A.
*
* Corresponding Author.
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Summary

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Marker Assisted Selection (MAS) based on additive effects associated with alleles at marker loci, estimated by linear regression of individual phenotype on the markers, was applied to characters with non-additive gene action and non-additive environment. The base population was the F2 generation of a cross between two inbred lines. Computer simulations of MAS were conducted for characters with dominance, epistasis and genotype-environment interaction approximated by the ‘additive-multiplicative’ model. MAS was more effective than purely phenotypic selection in all cases. The efficiency of MAS for characters with non-additive gene actionis comparable to (and for negative dominance even higher than) the efficiency of MAS for strictly additive characters. Environmental non-additivity, however, lowers the efficiency of MAS. Almost all results concerning the efficiency of MAS in our previoussimulations of purelyadditive traits are applicable to non-additive traits.

Type
Research Article
Information
Genetics Research , Volume 64 , Issue 2 , October 1994 , pp. 127 - 136
Copyright
Copyright © Cambridge University Press 1994

References

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