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A sex-linked anaemia in the mouse

Published online by Cambridge University Press:  14 April 2009

Manjit Singh Grewal
Manjit Singh Grewal
Affiliation:
Experimental Genetics Research Unit (Medical Research Council), University College London
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A sex-linked recessive anaemia (symbol sla) in the mouse is responsible for a rather uncharacteristic blood picture which persists virtually unchanged throughout life. The red cell count is reduced to about three-quarters of the normal value, the cells produced differ from normal ones by a slight reduction in the mean corpuscular Hb concentration and a slight reduction in the mean cell volume. As the mean cell diameter is more strongly reduced, it is concluded that the cells must be thicker than normal. There is a reduction of haemopoietic tissue both in the liver and in the bone marrow.

Type
Research Article
Information
Genetics Research , Volume 3 , Issue 2 , July 1962 , pp. 238 - 247
Copyright
Copyright © Cambridge University Press 1962

References

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