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The sequence of four structural and two regulatory methionine genes in the Salmonella typhimurium linkage map

Published online by Cambridge University Press:  14 April 2009

P. D. Ayling  and
K. F. Chater
P. D. Ayling
Affiliation:
Department of Genetics, University of Birmingham, England
K. F. Chater
Affiliation:
Department of Genetics, University of Birmingham, England
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Three-point transduction analysis was employed to determine the sequence of four structural and two regulatory methionine genes (metA, B, F, H and metI, J, respectively) on two apparently adjacent transduction fragments in Salmonella typhimurium. These fragments were subsequently orientated with respect to each other and the rest of the linkage map by the analysis of recombinants obtained in conjugation experiments. The following clockwise sequence of genes is proposed: -metJ-metB-metF-argF-thi-purD-metA-metI-metH-. The bearing of these results on the regulation of the metB–F and metA–H clusters is discussed.

Type
Research Article
Information
Genetics Research , Volume 12 , Issue 3 , December 1968 , pp. 341 - 354
Copyright
Copyright © Cambridge University Press 1968

References

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