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Selective fertilization at the T-locus of the mouse

Published online by Cambridge University Press:  14 April 2009

Nigel Bateman
Nigel Bateman
Affiliation:
Agricultural Research Council's Animal Breeding Research Organisation, Edinburgh 9
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Advantage was taken of a unique situation to test, with adequate controls, the assertion that male and female gametes conjugate at random. The data concern the aberrant locus T of the mouse, at which there are a number of t alleles that enter into the majority of effective spermatozoa of males heterozygous for one of them. Segregation in females is normal. Evidence is presented for one of these t alleles, tailless-Edinburgh (te), that conjugation between gametes was not at random when this gene was present in spermatozoa. When a choice of eggs was presented by heterozygous females, tailless-Edinburgh spermatozoa united more frequently with normal than with brachyury eggs and more frequently with brachyury than with tailless-Edinburgh eggs. The relevance of this finding is discussed in relation to expected equilibria of t alleles in closed populations. Other forms of selective fertilization are discussed and their genetic consequences compared.

Type
Research Article
Information
Genetics Research , Volume 1 , Issue 2 , July 1960 , pp. 226 - 238
Copyright
Copyright © Cambridge University Press 1960

References

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