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Salmonella hybrids containing genic material of multiple origins*

Published online by Cambridge University Press:  14 April 2009

F. B. Armstrong  and
George F. Sprague Jr
F. B. Armstrong
Affiliation:
Department of Biochemistry, North Carolina State University, Raleigh, North Carolina 27607 (U.S.A.)
George F. Sprague Jr
Affiliation:
Department of Biochemistry, North Carolina State University, Raleigh, North Carolina 27607 (U.S.A.)
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Summary

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Bacterial hybrids were produced to contain genetic material of Salmonella typhimurium, Escherichia coli, S. montevideo and S. abony origins. Analyses by transduction provide evidence that 6% of the original typhimurium genome has been replaced in the production of these hybrids. Although a number of biosynthetic pathways are affected by this gene substitution, the growth rate of these hybrids in minimal medium is unchanged. Supporting evidence for the close relatedness between S. typhimurium and the other three species is not observed in recombination studies. Available results favour the concept that differences in base sequences are responsible for the low frequency of recombination obtained in heterologous crosses.

Type
Research Article
Information
Genetics Research , Volume 17 , Issue 2 , April 1971 , pp. 133 - 138
Copyright
Copyright © Cambridge University Press 1971

References

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