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Salmonella hybrids containing genic material of multiple origins*

Published online by Cambridge University Press:  14 April 2009

F. B. Armstrong  and
George F. Sprague Jr
F. B. Armstrong
Affiliation:
Department of Biochemistry, North Carolina State University, Raleigh, North Carolina 27607 (U.S.A.)
George F. Sprague Jr
Affiliation:
Department of Biochemistry, North Carolina State University, Raleigh, North Carolina 27607 (U.S.A.)
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Summary

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Bacterial hybrids were produced to contain genetic material of Salmonella typhimurium, Escherichia coli, S. montevideo and S. abony origins. Analyses by transduction provide evidence that 6% of the original typhimurium genome has been replaced in the production of these hybrids. Although a number of biosynthetic pathways are affected by this gene substitution, the growth rate of these hybrids in minimal medium is unchanged. Supporting evidence for the close relatedness between S. typhimurium and the other three species is not observed in recombination studies. Available results favour the concept that differences in base sequences are responsible for the low frequency of recombination obtained in heterologous crosses.

Type
Research Article
Information
Genetics Research , Volume 17 , Issue 2 , April 1971 , pp. 133 - 138
Copyright
Copyright © Cambridge University Press 1971

References

REFERENCES

Adelberg, E. A., Mandel, M. & Chen, G. C. C. (1965). Optimal conditions for mutagenesis by N-methyl-N′-nitro-N-nitrosoguanidine in Escherichia coli K12. Biochemical and Biophysical Research Communications 18, 788–795.Google Scholar
Armstrong, F. B. (1967). Orientation and order of loci of the met-arg region in the Salmonella typhimurium linkage map. Genetics 56, 463–466.Google Scholar
Atkins, C. G. & Armstrong, F. B. (1969). Electrophoretic study of Salmonella typhimurium-Salmonella montevideo hybrids. Genetics 63, 775–779.CrossRefGoogle ScholarPubMed
Demerec, M. & Ohta, N. (1964). Genetic analyses of Salmonella typhimurium × Escherichia coli hybrids. Proceedings of the National Academy of Sciences U.S.A. 52, 317–323.Google Scholar
Enomoto, M. & Yamaguchi, S. (1969). Different frequencies of cotransduction of motC and Hl in Salmonella. Genetical Research 14, 45–52.Google Scholar
Falkow, S., Rownd, B. & Baron, L. S. (1962). Genetic homology between Escherichia coli K-12 and Salmonella. Journal of Bacteriology 84, 1303–1312.Google Scholar
Glatzer, L., LaBrie, D. A. & Armstrong, F. B. (1966). Transduction of Salmonella typhimurium-Salmonella montevideo hybrids. Genetics 54, 423–432.Google Scholar
Sanderson, K. F. (1970). A current linkage of Salmonella typhimurium. Bacteriological Reviews 34, 176–193.CrossRefGoogle ScholarPubMed
Zinder, N. D. (1960). Hybrids of Escherichia and Salmonella. Science 131, 813–815.Google Scholar