Hostname: page-component-586b7cd67f-vdxz6 Total loading time: 0 Render date: 2024-11-24T06:39:04.711Z Has data issue: false hasContentIssue false
  • English
  • Français

The recovery and preliminary examination of a temperature sensitive suppressor of the cryptocephal mutant of Drosophila melanogaster

Published online by Cambridge University Press:  14 April 2009

John C. Sparrow
John C. Sparrow
Affiliation:
Department of Biology, University of York, Heslington, York YO1 5DD
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The recovery of two EMS induced mutations which are dominant suppressors of the lethality of cryptocephal in Drosophila melanogaster are described. One of these mutations Su(crc)1 is described in detail. It maps very close to cryptocephal at 54·7 on the second chromosome and its suppression of cryptocephal is temperature-sensitive. Temperature shift experiments show that the temperature-sensitive period is from before the pupariation until 12 h post pupariation. The temperature-sensitive period of Su(crc)1 is discussed in relation to the expression of l(2)crc, head eversion and the timing of pupal chitin synthesis.

Type
Research Article
Information
Genetics Research , Volume 38 , Issue 3 , December 1981 , pp. 297 - 314
Copyright
Copyright © Cambridge University Press 1981

References

REFERENCES

Carpenter, J. M. (1950). A new semisynthetic food medium for Drosophila. Drosophila Information Service 24, 96–97.Google Scholar
Fristrom, J. W. (1964). Developmental and biochemical studies on the morphological mutant cryptocephal of Drosophila melanogaster. Ph.D. Thesis, Rockefeller Institute.Google Scholar
Fristrom, J. W. (1965). Development of the morphological mutant cryptocephal of Drosophila melanogaster. Genetics 52, 297–318.CrossRefGoogle ScholarPubMed
Hackman, R. H. (1976). The interactions of euticular proteins and some comments on their adaptation to function. In Insect Integument (ed. Hepburn, H. R.), Elsevier.Google Scholar
Hadorn, E. & Gloor, H. (1943). Cryptocephal, ein spätt wirkender Letalfaktor bei Drosophila melanogaster. Revue suisse de zoologie 50, 256–261.Google Scholar
Jenkins, J. B. (1967). Mutagenesis at a complex locus in Drosophila with a monofunctional alkylating agent ethylmethanesulfonate. Genetics 57, 783–793.CrossRefGoogle Scholar
Lewis, E. B. & Backer, F. (1968). Method of feeding ethylmethanesulfonate to Drosophila males. Drosophila Information Service 43, 193.Google Scholar
Lindsley, D. L. & Grell, E. H. (1968). Genetic variations of Drosophila melanogaster. Publications. Carnegie Institution of Washington, no. 627.Google Scholar
Rizki, M. T. M. (1960). The effects of glucosamine hydrochloride on the development of Drosophila melanogaster. Biological Bulletin. Marine Biological Laboratory, Woods Hole, Mass. 118, 308–314.CrossRefGoogle Scholar
Robertsoh, C. W. (1936). The metamorphosis of Drosophila melanogaster, including an accurately timed account of the principal morphological changes. Journal of Morphology 59, 351–399.CrossRefGoogle Scholar
Sparrow, J. C. & Wright, T. R. F. (1974). The selection for mutants in Drosophila melanogaster hypersensitive to α-methyl dopa, a dopa decarboxylase inhibitor. Molecular and General Genetics 130, 127–141.CrossRefGoogle ScholarPubMed
Wright, T. R. F., Hodgetts, R. B. & Sherald, A. F. (1976). The genetics of dopa decarboxylase in Drosophila melanogaster. I. Isolation and characterisation of deficiencies of the structural locus and the α-methyl dopa hypersensitive locus. Genetics 84, 267–285.CrossRefGoogle Scholar