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The rate of mutant substitution in populations with overlapping generations*

Published online by Cambridge University Press:  14 April 2009

Edward Pollak
Edward Pollak
Affiliation:
Department of Statistics, Iowa State University, Ames, Iowa 50011, USA
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We consider an age-structured population that is observed at times t = 0, 1, 2,…. It is assumed that for each t there is the same number of individuals of a particular sex and age group. Another assumption we make is that an offspring of a specified sex has at all times the same probability of having a parent of a particular age and sex. It is shown that the rate of substitution of neutral mutants is /L, where and L are respectively equal to the mean fraction of mutants among gametes succeeding in forming newborn individuals and the mean age of reproduction. This result also applies to monoecious populations. The substitution rate is also derived for advantageous mutants in a monoecious population. Once again, the mutation rate in the usual expression is replaced by /L. Implications of these results are discussed.

Type
Short Papers
Information
Genetics Research , Volume 40 , Issue 1 , August 1982 , pp. 89 - 94
Copyright
Copyright © Cambridge University Press 1982

References

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