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The production of translocations in spermatogonial cells of Drosophila by chloroethyl methanesulphonate (CB 1506)

Published online by Cambridge University Press:  14 April 2009

W. A. F. Watson
W. A. F. Watson
Affiliation:
Institute of Animal Genetics, Edinburgh 9

Extract

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Adult Drosophila males were injected with chloroethyl methanesulphonate and late progeny, tracing back to treated spermatogonia, were examined for sex-linked lethals and for translocations involving the X, Y, second and third chromosomes. A dose yielding about 20% sex-linked lethals produced 11 translocations in about 3500 tested chromosome sets (approx. 0·3%). This result is discussed in relation to the problem of chromosome rearrangements in different germ-cell stages.

Type
Research Article
Information
Genetics Research , Volume 3 , Issue 3 , November 1962 , pp. 467 - 471
Copyright
Copyright © Cambridge University Press 1962

References

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