Hostname: page-component-586b7cd67f-dsjbd Total loading time: 0 Render date: 2024-11-28T08:18:43.033Z Has data issue: false hasContentIssue false
  • English
  • Français

On the gene conversion model as a mechanism for maintenance of homogeneity in systems with multiple genomes

Published online by Cambridge University Press:  14 April 2009

Tomoko Ohta
Tomoko Ohta
Affiliation:
National Institute of Genetics, Mishima, 411, Japan
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The gene conversion model reported by Birky & Skavaril (1976) has been analytically studied by using the theory of diffusion models of Kimura (1964) in population genetics. It has been shown that the fate of new mutations in systems with multiple genomes may be satisfactorily treated by the diffusion model.

Type
Short paper
Information
Genetics Research , Volume 30 , Issue 1 , August 1977 , pp. 89 - 91
Copyright
Copyright © Cambridge University Press 1977

References

REFERENCES

Birky, C. W. Jr. & Skavaril, R. V. (1976). Maintenance of genetic homogeneity in systems with multiple genomes. Genetical Research 27. 249–265.CrossRefGoogle ScholarPubMed
Crow, J. F. & Kimura, M. (1970). An Introduction to Population Genetics Theory. New York, London: Harper and Row.Google Scholar
Hood, L. (1975). The organization, expression, and evolution of antibody genes and other multigene families. Annual Review of Genetics 9. 305–353.CrossRefGoogle ScholarPubMed
Kimura, M. (1964). Diffusion models in poulation genetics. Journal of Applied Probability 1. 177–232.CrossRefGoogle Scholar
Kimura, M. & Ohta, T. (1969 a) The average number of generations until fixation of a mutant gene in a finite population. Genetics 61. 763–771.CrossRefGoogle Scholar
Kiumra, M. & Ohta, T. (1969 b). The average number of generations until extinction of an individual mutant gene in a finite population. Genetics 63. 701–709.CrossRefGoogle Scholar
Ohta, T. (1976). A simple model for treating the evolution of multigene families. Nature 263. 74–76.CrossRefGoogle ScholarPubMed
Perelson, A. S. & Bell, G. I. (1977). Mathematical models for the evolution of multigene families by unequal corssing over. Nature 265. 304–310.CrossRefGoogle Scholar
Smith, G. P. (1974). Unequal crossover and the evolution of multigene familes. Cold Spring Harbor Symposia on Quantitative Biology 38. 507–513.CrossRefGoogle Scholar
Tartof, K. D. (1975). Redundant genes. Annual Review of Genetics 9. 355–385.CrossRefGoogle ScholarPubMed