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The number of loci affecting a quantitative trait in Drosophila melanogaster revealed by artificial selection

Published online by Cambridge University Press:  14 April 2009

Araceli Gallego  and
Carlos López-Fanjul
Araceli Gallego
Affiliation:
Departamento de Genética, Facultad de Biología, Universidad Complutense de Madrid, Madrid-3, Spain
Carlos López-Fanjul
Affiliation:
Departamento de Genética, Facultad de Biología, Universidad Complutense de Madrid, Madrid-3, Spain
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Summary

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Individual and within-full-sib family selection for low sternopleural bristle number was carried out for 17 generations, with six replicate lines for each selection method. Our results can be summarized as follows: (1) the response to selection was exhausted very quickly, (2) the additive variance of the selected lines declined rapidly, (3) the variation in response to selection decreased as selection progressed, (4) genetic differences among replicates at the selection limit were small, (5) individual selection resulted in a higher initial response than within-family selection, but similar limits were achieved with both procedures. These observations are consistent with the hypothesis that the pattern of response to selection is due to the segregation in the base population of only a few loci with large effects, at intermediate frequencies.

Type
Research Article
Information
Genetics Research , Volume 42 , Issue 2 , October 1983 , pp. 137 - 149
Copyright
Copyright © Cambridge University Press 1983

References

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