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A mathematical model of meiotic segregation in trisomics of yeast

Published online by Cambridge University Press:  14 April 2009

Stuart J. MacMartin  and
A. P. James
Stuart J. MacMartin
Affiliation:
Division of Biological Sciences, National Research Council of Canada, Ottawa, Ontario K1A 0R6
A. P. James
Affiliation:
Division of Biological Sciences, National Research Council of Canada, Ottawa, Ontario K1A 0R6

Summary

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Segregations at five loci on the left arm of chromosome VII and other data from published sources were used to test a new mathematical model of meiotic segregation in trisomics of the yeast Saccharomyces cerevisiae. Results support this model which predicts that non-centromere-linked genes in trivalent complexes segregate at random. The data indicate that bivalent–univalent complexes are infrequent in trisomics and that recombination between all three homologues is frequent in regions close to the centromere. A test of homologue interference produced no evidence that a crossover between two homologues has any influence on the probability that the same two homologues will be involved in an adjacent crossover.

Type
Research Article
Information
Genetics Research , Volume 33 , Issue 3 , June 1979 , pp. 189 - 204
Copyright
Copyright © Cambridge University Press 1979

References

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