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Mapping the adrenal lipid depletion gene of the AKR/J mouse strain

Published online by Cambridge University Press:  14 April 2009

B. A. Taylor  and
H. Meier
B. A. Taylor
Affiliation:
The Jackson Laboratory, Bar Harbor, Maine 04609
H. Meier
Affiliation:
The Jackson Laboratory, Bar Harbor, Maine 04609
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Summary

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The pattern of inheritance of the autosomal recessive adrenal lipid depletion (ald) allele among the AKXL recombinant inbred mouse lines, derived from a cross between AKR/J and C57L/J, revealed that the ald locus is located on chromosome 1 near the dipeptidase-1 (Dip-1) locus. The linkage was confirmed in a backcross generation and the gene order ln-Dip-1-ald was established.

Type
Research Article
Information
Genetics Research , Volume 26 , Issue 3 , December 1975 , pp. 307 - 312
Copyright
Copyright © Cambridge University Press 1975

References

REFERENCES

Arnesen, K. (1955). Constitutional difference in lipid content of adrenals in two strains of mice and their hybrids. Acta Endocrinologicia, Copenhagen 18, 396–401.Google ScholarPubMed
Arnesen, K. (1956). The adrenothymic constitution and susceptibility of leukemia in mice. Acta Pathologica et Microbiologica Scandinavica, Supplement, 109, 1–95.Google Scholar
Arnesen, K. (1974). Adrenocortical lipid depletion and leukemia in mice. Acta Pathologica et Microbiologica Scandinavica A, Supplement, 248, 15–19.Google Scholar
Bailey, D. W. (1971). Recombinant-inbred strains; an aid to finding identity, linkage, and function of histocompatibility and other genes. Transplantation 11, 419–422.CrossRefGoogle ScholarPubMed
Chapman, V. M., Ruddle, F. H. & Roderick, T. H. (1971). Linkage of isozyme loci in the mouse: Phosphoglucomutase-2 (Pgm-2), mitochondrial NADP malate dehydrogenase (Mod-2), and dipeptidase-1 (Dip-1). Biochemical Genetics 5, 101–111.CrossRefGoogle ScholarPubMed
Davisson, M. T. & Roderick, T. H. (1973). Chromosomal banding patterns of two paracentric inversions in mice. Cytogenetics and Cell Genetics 12, 398–403.CrossRefGoogle ScholarPubMed
Haldane, J. B. S. & Waddington, C. H. (1931). Inbreeding and linkage. Genetics 16, 357–374.CrossRefGoogle ScholarPubMed
Metcalf, D. (1960). Adrenal cortical function in high- and low-leukemia strains of mice. Cancer Research 20, 1347–1353.Google ScholarPubMed
Molne, D. (1969). Autoradiographic studies on the incorporation of 3H-uridine into the adrenal glands of mice with spontaneous adrenocortical lipid depletion. Acta Pathologica et Microbiologica Scandinavica 77, 369–378.CrossRefGoogle Scholar
Taylor, B. A. (1972). Genetic relationships between inbred strains of mice. Journal of Heredity 63, 83–86.CrossRefGoogle ScholarPubMed
Taylor, B. A., Meier, H. & Myers, D. D. (1971). Host-gene control of C-type RNA tumor virus: Inheritance of the group-specific antigen of murine leukemia virus. Proceedings of the National Academy of Science, U.S.A. 68, 3190–3194.CrossRefGoogle ScholarPubMed