Hostname: page-component-586b7cd67f-rdxmf Total loading time: 0 Render date: 2024-11-28T01:07:56.579Z Has data issue: false hasContentIssue false

Mapping of ochre suppressors in Escherichia coli

Published online by Cambridge University Press:  14 April 2009

Gudmundur Eggertsson
Affiliation:
Department of Radiology, Yale University, New Haven, Connecticut, U.S.A., and The International Laboratory of Genetics and Biophysics, Naples, Italy*
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Genetic mapping of suppressors of the ilv-188 mutation is described. Suppressors of this mutation have been mapped at four ochre suppressor loci: sup L, sup M, sup N and sup O. The ochre suppressor described by Brenner & Beckwith is shown not to suppress ilv-188 whereas the suppressor described by the same authors suppresses ilv-188 and may represent the same locus as supO suppressors. The mapping by P1 transduction of the sup L, sup M and sup N loci is described.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1968

References

REFERENCES

Adelberg, E. A. & Burns, S. (1960). Genetic variation in the sex factor of Escherichia coli. J. Bact. 79, 321330.CrossRefGoogle ScholarPubMed
Brenner, S. & Beckwith, J. R. (1965). Ochre mutants, a new class of suppressible nonsense mutants. J. molec. Biol. 13, 629637.CrossRefGoogle Scholar
Brenner, S., Kaplan, S. & Stretton, A. O. W. (1966). Identity of N2 and ochre nonsense mutants. J. molec. Biol. 19, 574575.CrossRefGoogle ScholarPubMed
Demerec, M., Adelberg, A., Clark, A. J. & Hartman, P. (1966). A proposal for a uniform nomenclature in bacterial genetics. Genetics 54, 6176.Google Scholar
Eggertsson, G. & Adelberg, E. A. (1965). Map positions and specificities of suppressor mutations in Escherichia coli K-12. Genetics 52, 319340.CrossRefGoogle ScholarPubMed
Gallucci, E. & Garen, A. (1966). Suppressor genes for nonsense mutations. II. The Su-4 and Su-5 suppressor genes of Escherichia coli. J. molec. Biol. 15, 193200.CrossRefGoogle ScholarPubMed
Lennox, E. S. (1955). Transduction of linked genetic characters of the host by bacteriophage P1. Virology 1, 190206.CrossRefGoogle ScholarPubMed
McFall, E. (1967). Mapping of the D-serine deaminase region in Escherichia coli K-12. Genetics 55, 9199.CrossRefGoogle ScholarPubMed
Rothman, J. L. (1965). Transduction studies on the relation between prophage and host chromosome. J. molec. Biol. 12, 892912.Google Scholar
Signer, E. R., Beckwith, J. R. & Brenner, S. (1965). Mapping of suppressor loci in Escherichia coli. J. molec. Biol. 14, 153166.CrossRefGoogle ScholarPubMed
Taylor, A. L. & Thoman, M. S. (1964). The genetic map of Escherichia coli K-12. Genetics 50, 659677.Google Scholar