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Mapping an invisible lethal in the mouse

Published online by Cambridge University Press:  14 April 2009

Margaret E. Wallace
Margaret E. Wallace
Affiliation:
Department of Genetics, University of Cambridge
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Summary

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An effective breeding policy is described for detecting linkage in the mouse, for an ante-natal lethal from crosses of heterozygotes with stocks homozygous for several linked recessive markers. A method of analysing the ensuing data is described, together with a method of estimating the map distance to close markers. A practical illustration is described, involving an ante-natal lethal obtained from a colony of wild mice and a four fold recessive chromosome 2 marker stock.

Type
Research Article
Information
Genetics Research , Volume 27 , Issue 1 , February 1976 , pp. 3 - 10
Copyright
Copyright © Cambridge University Press 1976

References

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