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Lysogenization by phage P22 carrying amber mutations in Genes 12 and 18

Published online by Cambridge University Press:  14 April 2009

Amiram Ronen  and
Myron Levine
Amiram Ronen
Affiliation:
Department of Genetics, The Hebrew University of Jerusalem, Israel, and the Department of Human Genetics, The University of Michigan, Ann Arbor, Michigan 48109, U.S.A.
Myron Levine
Affiliation:
Department of Genetics, The Hebrew University of Jerusalem, Israel, and the Department of Human Genetics, The University of Michigan, Ann Arbor, Michigan 48109, U.S.A.
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Summary

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Temperature-sensitive mutants in genes 12 and 18 of phage P22 show recessive DNA-negative phenotypes, but dominant integration-negative phenotypes. In contrast, am mutants in genes 12 and 18 are recessive for both DNA synthesis and lysogeny. The data are interpreted to indicate that the active forms of these two gene products are multimers.

Type
Research Article
Information
Genetics Research , Volume 27 , Issue 2 , April 1976 , pp. 335 - 337
Copyright
Copyright © Cambridge University Press 1976

References

REFERENCES

Bode, W., Dopatka, H. D. & Prell, H. H. (1973). Functional classification of P22 amber mutants. Molecular and General Genetics 127, 341–347.CrossRefGoogle ScholarPubMed
Levine, M. & Schott, C. (1971). Mutations of phage P22 affecting phage DNA synthesis and lysogenization. Journal of Molecular Biology 62, 53–64.CrossRefGoogle ScholarPubMed