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Linkage disequilibrium in experimental populations of Drosophila simulans: a test of the random drift hypothesis

Published online by Cambridge University Press:  14 April 2009

Catherine Montchamp-Moreau  and
Mariano Katz
Catherine Montchamp-Moreau
Affiliation:
Unité Associée 693 du C.N.R.S., Génétique des populations, Universités Paris 6 et Paris 7, 75251 Paris Cédex 05, France
Mariano Katz
Affiliation:
Unité Associée 693 du C.N.R.S., Génétique des populations, Universités Paris 6 et Paris 7, 75251 Paris Cédex 05, France
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Linkage disequilibrium between five polymorphic enzymic loci of the third chromosome (Esterase-6, Phosphoglucomutase, Esterase-C, Aldehyde Oxidase and Acid Phosphatase) was studied in experimental populations of Drosophila simulans. Gametic data were obtained by mating sampled males with homozygous females at the five loci. Four cage populations were initiated with flies caught from natural populations. Extensive linkage disequilibrium was detected after 25 or 34 generations. The effective size of these populations was estimated about 400. Monte-Carlo simulations were performed in order to determine whether the observed disequilibria could be due to genetic drift. The observed probability distribution of the experimental values of r (the gametic correlation coefficient) was consistent with the distribution expected under random genetic drift. Our results are thus in accordance with the neutralist hypothesis.

Type
Research Article
Information
Genetics Research , Volume 50 , Issue 3 , December 1987 , pp. 187 - 193
Copyright
Copyright © Cambridge University Press 1987

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